Figure 1
From: The LCMV gp33-specific memory T cell repertoire narrows with age
Pinwheel depiction of the TCRVβ usage of gp33-tetramer+cells following infection with LCMV. Naive represents the unimmunized repertoire. Each pinwheel represents the distribution of TCRVβ from tetramer sorted cells from a single mouse. Two mice were tested at 26 months, designated #1 and #2. The number of cells sequenced in each pinwheel is: naïve, 55; 23 Days, 136; 15 months, 705; 22 months, 187; months 26 mouse 1, 60; 26 months mouse 2, 64. The entire CDR3 sequences have been deposited in Genbank, Accession numbers: [Genbank:JX277204 – JX277543].