From: Uremia causes premature ageing of the T cell compartment in end-stage renal disease patients
 | End-stage renal disease patients not receiving renal replacement therapy | End-stage renal disease patients receiving renal replacement therapy | Healthy controls | |||
---|---|---|---|---|---|---|
Group | Young | Old | Young | Old | Young | Old |
Number of individuals | 22 | 33 | 49 | 49 | 55 | 65 |
Age in Years | 33.5 ± 9.6* | 64.4 ± 6.3* | 35.7 ± 8.5* | 63.1 ± 8.7* | 38.4 ± 7.9* | 63.5 ± 7.5* |
Male | 77.3% | 60.6% | 55.1% | 71.4% | 49.1% | 38.5% |
CMV positive | 54.5% | 51.2% | 59.2% | 53.1% | 50.9% | 49.2% |
Hemodialysis | Â | Â | 25 | 32 | Â | Â |
Peritoneal dialysis | Â | Â | 24 | 17 | Â | Â |
Duration of RRT (years) | Â | Â | 4.30 (0.1 - 22)** | 2.76 (0.2 - 18)** | Â | Â |
Underlying kidney disease | Â | Â | Â | Â | Â | Â |
- Hypertensive nephropathy | 13.6% | 27.2% | 20.8% | 30.6% | Â | Â |
- Primary glomerulopathy | 31.8% | 18.2% | 18.8% | 18.4% | Â | Â |
- Diabetic nephropathy | 0% | 21.2% | 2.1% | 8.2% | Â | Â |
- Polycystic kidney disease | 9.1% | 9.0% | 0% | 2.0% | Â | Â |
- Reflux nephropathy | 18.2% | 3.0% | 14.6% | 4.1% | Â | Â |
- Other | 9.1% | 15.2% | 20.9% | 8.2% | Â | Â |
- Unknown | 18.2% | 6.0% | 22.9% | 28.6% | Â | Â |