Table 1 Gender-dependent immune pathways or molecules that causes different disease susceptibility in men and women
Gender dependent immune pathways or molecules | Disease susceptibility | References |
|---|---|---|
Caspase-12 long variant | infectious diseases | Yeretssian G, Proc Natl Acad Sci, 2009, 106:9016 |
Glucocorticoid receptor pathways | infectious diseases | Wynne O, Stress, 2011, 14:247 |
Sulfur-dependent detoxification pathways | autism | Al-Yafee YA, BMC Neurol, 2011, 11:139 |
MyD88-dependent pathway | type 1 diabetes | Sheng H J, Immunol, 2011, 187:1591 |
STAT5-dependent pathway | human growth disorders | Davey HW, Am J Hum Genet, 1999, 65:959 |
Toll-like receptor 4 | chronic pain | Sorge RE, J Neurosci, 2011, 31:15450 |
B7-H1-dependent pathway | melanoma | Lin PY, J Immunol, 2010, 185:2747 |
PARP-1-dependent pathway | lupus nephritis | Caricchio R, NIH RePORTER, 2012, 08 01 |
HLA-DRB1*0401 and HLA-DQ8 | arthritis | Behrens M, J Autoimmun, 2011, 37:95 |
Rac1, NOX, ROS | kaposi's sarcoma | Goldschmidt CPJ, NIH RePORTER, 2010, 05 01 |
CTLA4 | hepatitis C | Schott E, J Hepatol. 2007, 46:372 |
Toll-like receptor 7 | chronic HCV-infection | Schott E, J Hepatol, 2007, 47:203 |
Aim2 and p202 proteins | systemic lupus erythematosus | Panchanathan R, Mol Immunol, 2011, 49:273 |
Retinoid x receptor alpha | hepatocellular carcinogenesis | Guo M, BMC Genomics, 2008, 9:403 |
MAPK signaling | systemic lupus erythematosus | Xie H, Arthritis Rheum; 2011, 63:2425 |