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Table 4 Cytokine data from our studies in Sicilian population

From: Genetics of longevity. Data from the studies on Sicilian centenarians

Gene Genotypes Centenarians Young controls (< 55 years)   P
   N = 31 males N = 161 males   
IL-10 -1082GG 18 (58%) 55 (34%)   < 0.025 [61]
  -1083GA 9 (29%) 88 (55%)   
  -1082AA 4 (13%) 18 (11%)   
   N = 72 males N = 115 males   
IL-10 -1082GG 33 (46%) 32(28%)   0.019 [62]
  -1083GA 34(47%) 64(56%)   
  -1082AA 5(7%) 19(16%)   
   Centenarians Young controls (< 55 years) MI patients (< 55 years) P
   N = 52 males N = 110 males N = 90 males  
IL-10 -1082GG 25 (48.1%) 26(23.6%) 17 (18.9%) 0.003 [63]
  -1083GA 23 (44.2%) 56 (50.9%) 29 (32.2%)  
  -1082AA 6(11.5%) 28 (25.5%) 44 (48.9%)  
Genes Alleles of SNP Centenarians Young controls (< 55 years)   P
   N = 142 females N = 90 females   
IFN-γ +874 T 102 (35.9%) 85 (47.2%)   0.02 [60]
  + 874A 182 (64.1%) 95 (52.8%)