Table 2 Allelic and genotypic distribution of subjects for the present analyses at baseline
Gene | rs No | Allele1) | Allele N= 3914 | Number (%) | Genotype | N= 1957 | Number (%) |
|---|---|---|---|---|---|---|---|
Tumor necrosis factor-α (TNF-α) | rs1800630 | A (C) | C | A | CC | CA | AA |
3229 (82.5) | 685 (17.5) | 1420 (72.5) | 389 (19.9) | 148 (7.6) | |||
Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) | rs1061624 | A (G) | G | A | GG | GA | AA |
1916 (49.0) | 1998 (51.0) | 473 (24.2) | 970 (49.6) | 514 (26.2) | |||
Interleukin-1A (IL1A) | rs1800587 | T (C) | C | T | CC | CT | TT |
3525 (90.1) | 389 (9.9) | 1587 (81.1) | 351 (17.9) | 19 (1.0) | |||
Interleukin-1B (IL1B) | rs16944 | T (C) | C | T | CC | CT | TT |
2094 (53.5) | 1820 (46.5) | 546 (27.9) | 1002 (51.2) | 409 (20.9) | |||
Interleukin 4 receptor (IL-4R) | rs1801275 | G (A) | A | G | AA | AG | GG |
3375 (86.2) | 539 (13.8) | 1454 (74.3) | 467 (23.9) | 36 (1.8) | |||
Interleukin-6 (IL-6) | rs1800796 | G (C) | C | G | CC | CG | GG |
2969 (75.9) | 945 (24.1) | 1134 (58.0) | 701 (35.8) | 122 (6.2) | |||
Interleukin-10 (IL-10) | rs1800872 | C (A) | A | C | AA | AC | CC |
2648 (67.7) | 1266 (32.3) | 896 (45.8) | 856 (43.7) | 205 (10.5) | |||
Interleukin 1 receptor-associated kinase-1 (IRAK-1) | rs1059702 | C (T) | T | C | TT | TC | CC |
3000 (76.6) | 914 (23.4) | 1312 (67.0) | 376 (19.2) | 269 (13.8) | |||
C-reactive protein 2 (CRP2) | rs1130864 | T (C) | C | T | CC | CT | TT |
3670 (93.8) | 244 (6.2) | 1721 (87.9) | 228 (11.7) | 8 (0.4) |