Gene | rs No | Crude: model 1 | Adjusted: model 2 | Adjusted: model 3 | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Odds ration | 95% CI | p value | Odds ration | 95% CI | p value | Odds ration | 95% CI | p value | ||
TNF- α | rs1800630 | |||||||||
Hearing impairment criteria | ||||||||||
PTABE 1)>25 dB | 1.120 | 0.979-1.281 | 0.100 | 1.192 | 1.020-1.392 | 0.027 | 1.172 | 1.005-1.367 | 0.044 | |
PTABE 40 dB | 1.090 | 0.885-1.344 | 0.417 | 1.109 | 0.884-1.390 | 0.372 | 1.106 | 0.884-1.384 | 0.380 | |
TNFRSF1B | rs1061624 | |||||||||
PTABE >25 dB | 1.151 | 1.021-1.297 | 0.022 | 1.210 | 1.052-1.393 | 0.008 | 1.211 | 1.053-1.392 | 0.007 | |
PTABE >40 dB | 1.272 | 1.052-1.538 | 0.013 | 1.293 | 1.045-1.599 | 0.018 | 1.275 | 1.026-1.584 | 0.028 | |
IL1A | rs1800587 | |||||||||
PTABE >25 dB | 1.093 | 0.894-1.335 | 0.386 | 1.061 | 0.845-1.331 | 0.611 | 1.070 | 0.855-1.339 | 0.557 | |
PTABE >40 dB | 0.975 | 0.692-1.373 | 0.885 | 0.946 | 0.660-1.354 | 0.760 | 0.956 | 0.667-1.371 | 0.807 | |
IL1B | rs16944 | |||||||||
PTABE >25 dB | 0.941 | 0.834-1.060 | 0.316 | 0.915 | 0.796-1.052 | 0.212 | 0.920 | 0.801-1.057 | 0.238 | |
PTABE >40 dB | 0.924 | 0.762-1.121 | 0.422 | 0.960 | 0.774-1.190 | 0.706 | 0.945 | 0.760-1.174 | 0.608 | |
IL-4 | Rrs1801275 | |||||||||
PTABE >25 dB | 0.986 | 0.829-172 | 0.872 | 1.038 | 0.851-1.265 | 0.715 | 1.031 | 0.847-1.255 | 0.761 | |
PTABE >40 dB | 0.968 | 0.729-1.85 | 0.822 | 1.010 | 0.746-1.367 | 0.949 | 1.050 | 0.774-1.424 | 0.756 | |
IL-6 | rs1800796 | |||||||||
PTABE >25 dB | 1.011 | 0.881-1.161 | 0.872 | 1.083 | 0.924-1.269 | 0.327 | 1.079 | 0.922-1.262 | 0.343 | |
PTABE >40 dB | 1.034 | 0.829-1.289 | 0.770 | 1.042 | 0.822-1.320 | 0.734 | 1.056 | 0.833-1.339 | 0.651 | |
IL-10 | rs1800872 | |||||||||
PTABE >25 dB | 0.981 | 0.864-1.114 | 0.764 | 0.983 | 0.844-1.145 | 0.826 | 0.973 | 0.838-1.131 | 0.725 | |
PTABE >40 dB | 0.887 | 0.714-1.102 | 0.280 | 0.860 | 0.572-1.101 | 0.231 | 0.834 | 0.651-1.070 | 0.153 | |
IRAK-1 | rs1059702 | |||||||||
PTABE >25 dB | 1.026 | 0.912-1.55 | 0.666 | 1.012 | 0.889-1.151 | 0.862 | 1.010 | 0.888-1.148 | 0.885 | |
PTABE >40 dB | 0.887 | 0.718-1.097 | 0.268 | 0.8161 | 0.707-1.051 | 0.141 | 0.869 | 0.713-1.058 | 0.162 | |
CRP2 | rs1130864 | |||||||||
PTABE >25 dB | 0.976 | 0.758-1.257 | 0.81 | 1.099 | 0.816-1.479 | 0.535 | 1.092 | 0.817-1.461 | 0.552 | |
PTABE >40 dB | 0.924 | 0.624-1.363 | 0.692 | 1.081 | 0.711-1.643 | 0.715 | 1.113 | 0.726-1.705 | 0.623 |