Figure 3From: A G613A missense in the Hutchinson’s progeria lamin A/C gene causes a lone, autosomal dominant atrioventricular blockFrequency analysis of controls with PCR for rs56816490. Image of electrophoretic analysis of PCR validation amplifications of genomic DNA from pedigree subjects (III:2 and IV:4) and independent controls. Amplification of the mutated allele of LMNA/C (G613A) is present only in the affected subject (IV:4, the proband).Back to article page