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Table 1 Patient characteristics

From: Age-related limitations of interleukin-6 in predicting early mortality in acute ST-elevation myocardial infarction

 

Survivors (n = 148)

Non-survivors (n = 10)

P

Demographic parameters

Age, yrs

57 (50–64)

72 (68–80)

0.0001

Gender (men,%)

70

72

1.00

BMI (kg/m2)

26.0 (24.1-28.0)

25.0 (21.0-26.8)

0.27

Medical history

Hypertension,%

45

45

1.00

Diabetes,%

13

20

0.63

Smoking,%

65

30

0.042

Previous angina,%

20

70

0.0006

Prior MI,%

9

0

0.60

Current disease

Time to treatment, hrs

3.5 (2.5-5.0)

7.0 (4.0-9.0)

0.003

Max. QRS duration, ms

90 (80–100)

100 (93–120)

0.60

EF,%

61 (50–72)

56 (45–63)

0.003

Killip-Kimball class >1,%

3

64

0.0001

Angiographic parameters

>1 vessel affected,%

47

90

0.016

TIMI (0–2) before PCI,%

93

100

1.00

TIMI (0–2) after PCI,%

32

60

0.091

CTFG

24 (30–32)

25 (31–100)

0.019

MBG (0–1),%

32

60

0.091

Abciximab,%

26

70

0.008

PCI complications,%

5

40

0.009

Laboratory findings

CPK, U/l

1649 (740–2699)

3473 (2544–4885)

0.011

CK-MB, U/l

159 (62–273)

371 (271–520)

0.014

cTnI (μg/l)

16 (3–45)

7 (1–30)

0.62

Total cholesterol, mmol/l

5.9 (5.2-7.2)

6.2 (5.6-6.8)

0.78

LDL cholesterol, mmol/l

3.9 (3.2-4.8)

3.9 (3.4-4.4)

0.93

HDL cholesterol, mmol/l

1.4 (1.2-1.7)

1.3 (1.1-1.7)

0.64

Triglycerides, mmol/l

1.5 (1.1-2.2)

1.6 (0.9-2.6)

0.93

Glucose, mmol/l

6.4 (5.6-7.7)

9.3 (7.3-14.1)

0.002

CRP (mg/l)

2.2 (0.7-6.3)

2.0 (1.3-6.0)

0.74

Creatinine, μmol/l

84 (73–96)

94 (74–127)

0.26

IL-6, pg/ml

2.0 (0.1-9.0)

8.5 (2.5-20.0)

0.032

sIL-6R, ng/ml

53.0 (41.6-66.2)

51.1 (32.9-65.1)

0.58

  1. Abbreviations: BMI body mass index, CK-MB creatine kinase-myocardial band isoform, CPK creatine phosphokinase, CRP C-reactive protein, CTFC corrected TIMI frame count, EF ejection fraction, HDL high density lipoprotein, IL-6 interleukin-6, IL-6sR interleukin-6 soluble receptor, LDL low density lipoprotein, MBG myocardial blush grade, TIMI thrombolysis in myocardial infarction scale.
  2. Comparisons were made between patients who survived and those who died within 30 days after STEMI. Values are the medians (and interquartile ranges) or percentages.