Figure 1
From: The interplay between immune maturation, age, chronic viral infection and environment
Longitudinal changes in major blood population during the first year of life. The graphs show longitudinal changes in the absolute frequencies of neutrophils (A), monocytes (B), or lymphocytes (C) in peripheral blood of SPF-2 infant macaques from birth to 1 year. Panels (D) to (F) illustrate the changes of B cells, T cells, and the CD4+ and CD8+T cell populations, respectively, in the first year of life. Data are represented as mean absolute numbers of 23 SPF-2 infants ± SEM per microliter of blood. Panel (G) shows the significant decline in the CD4:CD8 T cell ratio from birth to 3 months of age, after which the ratio remained stable throughout week 40. Boxplot horizontal bars indicate the median value in each age group.