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Table 3 Peripheral blood populations in adolescent SPF-2 and non-SPF macaques

From: The interplay between immune maturation, age, chronic viral infection and environment

Cell population

Median cell numbers/ μl blood (Minimum-Maximum)

 

SPF-2 Adolescents

Non-SPF Adolescents

SPF-2 vs. Non-SPF a

(n = 30)

(n = 50)

Neutrophils

10502

9576

NSb

(6667–18502)

(1936–21156)

Monocytes

328

392

NS

(202–855)

(70–1620)

Lymphocytes

1949

3037

p < 0.0001

(1107–3088)

(756–8073)

B Cells

474

1445

p < 0.0001

(136–808)

(269–4317)

T Cells

1257

1155

NS

(336–1899)

(311–3730)

CD4+ T

828

753

NS

(459–1319)

(195–2202)

CD8+ T

397

310

p = 0.0247

 

(209–1109)

(99–1401)

CD4:CD8 Ratio

2.0

2.4

p = 0.0132

(0.7-3.8)

(1.4-4.0)

  1. aData were compared by Mann–Whitney test. bNS = non-significant.