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Table 3 Intragroup comparisons between CD117+ and CD117- cases for total CD34+ cells and CD34+ fractions

From: Correlation between CD117+ myeloma plasma cells and hematopoietic progenitor cells in different categories of patients

Group

 

CD117+

CD117-

p value

MGUS

Tot CD34+

1.47

1.19

NS

  

(0.50–2.46)

(0.30–1.63)

 

CD34 + CD19-

95.49

86.72

NS

  

(82.58–97.99)

(85.73–96.34)

 

CD34 + CD19+

4.51

13.28

NS

  

(2.01–17.42)

(3.66–14.27)

 

Ratio

21.17

6.53

NS

  

(4.74–48.75)

(6.01–26.32)

Therapy

Tot CD34+

0.73

1.83

0.013

  

(0.14–2)

(0.85–2.84)

 

CD34 + CD19-

78.71

70.97

NS

  

(33.91–98.71)

(62.86–91.42)

 

CD34 + CD19+

21.29

29.04

NS

  

(1.29–66.09)

(8.58–37.14)

 

Ratio

4.27

2.50

NS

  

(0.51–76.52)

(1.69–10.66)

New

Tot CD34+

1.80

0.56

0.018

  

(0.49–2.61)

(0.06–1.22)

 

CD34 + CD19-

82.42

94.59

0.003

  

(74.98–87.70)

(90–98.89)

 

CD34 + CD19+

17.58

5.41

0.003

  

(12.30–25.02)

(1.11–10)

 

Ratio

4.69

17.48

0.003

  

(3–7.13)

(9–89.09)

Progressive

Tot CD34+

0.80

0.60

NS

  

(0.22–0.87)

(0.23–0.62)

 

CD34 + CD19-

88.75

77.88

0.036

  

(80.79–94.83)

(75.73–80.77)

 

CD34 + CD19+

11.25

22.12

0.036

  

(5.17–19.21)

(19.23–24.27)

 

Ratio

7.89

3.52

0.036

  

(4.21–18.34)

(3.12–4.20)

  1. Results are expressed as median percentage (range)
  2. Tot CD34+, total CD34+ hematopoietic progenitor cells; CD34 + CD19-, fraction of CD34 + CD19- cells (out of total CD34+ cells); CD34 + CD19+, fraction of CD34 + CD19+ cells (out of total CD34+ cells); Ratio, CD34 + CD19-/CD34 + CD19+ cellular fraction ratio
  3. The Mann-Whitney U-test was used for this analysis