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Fig. 3 | Immunity & Ageing

Fig. 3

From: Comprehensive circular RNA profiling reveals that circular RNA100783 is involved in chronic CD28-associated CD8(+)T cell ageing

Fig. 3

Schematic strategy of pooling circRNA microarray profiles. Eight microarrays are depicted by 8 green circles. After eight microarray profiles were individually acquired, three microarray profiles detecting CD28(+)CD8(+)T cells from three age-dependent elderly subgroups were pooled as Q1,and three microarray profiles detecting CD28(-)CD8(+)T cells from three age-dependent elderly subgroups were pooled as Q2. Consequently, four cross-group comparisons were performed as: Comparison1 (C1:Q1 vs Q2 indicating CD28(+)CD8(+) vs CD28(-)CD8(+) T cells in the elderly); Comparison2 (C2: Q3 vs Q4 indicating CD28(+)CD8(+) vs CD28(-)CD8(+)T cells in the adult); Comparison 3 (C3:Q1 vs Q3 indicating CD28(+)CD8(+)T cells in the elderly vs in the adult); and Comparison4 (C4: Q2 vs Q4 indicating CD28(-)CD8(+)T cells in the elderly vs in the adult)

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