TY - JOUR AU - Reis, Maria Danielma dos Santos AU - Csomos, Krisztian AU - Dias, Luciene Paschoal Braga AU - Prodan, Zsolt AU - Szerafin, Tamas AU - Savino, Wilson AU - Takacs, Laszlo PY - 2015 DA - 2015/10/29 TI - Decline of FOXN1 gene expression in human thymus correlates with age: possible epigenetic regulation JO - Immunity & Ageing SP - 18 VL - 12 IS - 1 AB - Thymic involution is thought to be an important factor of age related immunodeficiency. Understanding the molecular mechanisms of human thymic senescence may lead to the discovery of novel therapeutic approaches aimed at the reestablishment of central and peripheral T cell repertoire. SN - 1742-4933 UR - https://doi.org/10.1186/s12979-015-0045-9 DO - 10.1186/s12979-015-0045-9 ID - Reis2015 ER -