TY - JOUR AU - Muller, L. AU - Fulop, T. AU - Pawelec, G. PY - 2013 DA - 2013// TI - Immunosenescence in vertebrates and invertebrates JO - Immun Ageing VL - 10 UR - https://doi.org/10.1186/1742-4933-10-12 DO - 10.1186/1742-4933-10-12 ID - Muller2013 ER - TY - JOUR AU - Linton, P. J. AU - Dorshkind, K. PY - 2004 DA - 2004// TI - Age-related changes in lymphocyte development and function JO - Nat Immunol VL - 5 UR - https://doi.org/10.1038/ni1033 DO - 10.1038/ni1033 ID - Linton2004 ER - TY - JOUR AU - Pawelec, G. PY - 2012 DA - 2012// TI - Hallmarks of human “immunosenescence”: adaptation or dysregulation? JO - Immun Ageing VL - 9 UR - https://doi.org/10.1186/1742-4933-9-15 DO - 10.1186/1742-4933-9-15 ID - Pawelec2012 ER - TY - JOUR AU - Fulop, T. AU - Larbi, A. AU - Pawelec, G. PY - 2013 DA - 2013// TI - Human T cell aging and the impact of persistent viral infections JO - Front Immunol VL - 4 UR - https://doi.org/10.3389/fimmu.2013.00271 DO - 10.3389/fimmu.2013.00271 ID - Fulop2013 ER - TY - JOUR AU - Blankenberg, S. AU - Rupprecht, H. J. AU - Bickel, C. AU - Espinola-Klein, C. AU - Rippin, G. AU - Hafner, G. PY - 2001 DA - 2001// TI - Cytomegalovirus infection with interleukin-6 response predicts cardiac mortality in patients with coronary artery disease JO - Circulation VL - 103 UR - https://doi.org/10.1161/01.CIR.103.24.2915 DO - 10.1161/01.CIR.103.24.2915 ID - Blankenberg2001 ER - TY - JOUR AU - Bentz, G. L. AU - Yurochko, A. D. PY - 2008 DA - 2008// TI - Human CMV infection of endothelial cells induces an angiogenic response through viral binding to EGF receptor and beta1 and beta3 integrins JO - Proc Natl Acad Sci U S A VL - 105 UR - https://doi.org/10.1073/pnas.0800037105 DO - 10.1073/pnas.0800037105 ID - Bentz2008 ER - TY - JOUR AU - Chen, S. AU - Craen, A. J. AU - Raz, Y. AU - Derhovanessian, E. AU - Vossen, A. C. AU - Westendorp, R. G. PY - 2012 DA - 2012// TI - Cytomegalovirus seropositivity is associated with glucose regulation in the oldest old. Results from the Leiden 85-plus study JO - Immun Ageing VL - 9 UR - https://doi.org/10.1186/1742-4933-9-18 DO - 10.1186/1742-4933-9-18 ID - Chen2012 ER - TY - JOUR AU - Wikby, A. AU - Nilsson, B. O. AU - Forsey, R. AU - Thompson, J. AU - Strindhall, J. AU - Lofgren, S. PY - 2006 DA - 2006// TI - The immune risk phenotype is associated with IL-6 in the terminal decline stage: findings from the Swedish NONA immune longitudinal study of very late life functioning JO - Mech Ageing Dev VL - 127 UR - https://doi.org/10.1016/j.mad.2006.04.003 DO - 10.1016/j.mad.2006.04.003 ID - Wikby2006 ER - TY - JOUR AU - Adriaensen, W. AU - Derhovanessian, E. AU - Vaes, B. AU - Pottelbergh, G. AU - Degryse, J. M. AU - Pawelec, G. PY - 2015 DA - 2015// TI - CD4:8 ratio >5 is associated with a dominant naive T-cell phenotype and impaired physical functioning in CMV-seropositive very elderly people: results from the BELFRAIL study JO - J Gerontol A Biol Sci Med Sci VL - 70 UR - https://doi.org/10.1093/gerona/glu018 DO - 10.1093/gerona/glu018 ID - Adriaensen2015 ER - TY - JOUR AU - Deusch, K. AU - Luling, F. AU - Reich, K. AU - Classen, M. AU - Wagner, H. AU - Pfeffer, K. PY - 1991 DA - 1991// TI - A major fraction of human intraepithelial lymphocytes simultaneously expresses the gamma/delta T cell receptor, the CD8 accessory molecule and preferentially uses the V delta 1 gene segment JO - Eur J Immunol VL - 21 UR - https://doi.org/10.1002/eji.1830210429 DO - 10.1002/eji.1830210429 ID - Deusch1991 ER - TY - JOUR AU - Holtmeier, W. AU - Kabelitz, D. PY - 2005 DA - 2005// TI - Gammadelta T cells link innate and adaptive immune responses JO - Chem Immunol Allergy VL - 86 UR - https://doi.org/10.1159/000086659 DO - 10.1159/000086659 ID - Holtmeier2005 ER - TY - JOUR AU - Beckman, E. M. AU - Porcelli, S. A. AU - Morita, C. T. AU - Behar, S. M. AU - Furlong, S. T. AU - Brenner, M. B. PY - 1994 DA - 1994// TI - Recognition of a lipid antigen by CD1-restricted alpha beta + T cells JO - Nature VL - 372 UR - https://doi.org/10.1038/372691a0 DO - 10.1038/372691a0 ID - Beckman1994 ER - TY - JOUR AU - Libero, G. AU - Mori, L. PY - 2003 DA - 2003// TI - Self glycosphingolipids: new antigens recognized by autoreactive T lymphocytes JO - News Physiol Sci VL - 18 ID - Libero2003 ER - TY - JOUR AU - Hayday, A. C. PY - 2000 DA - 2000// TI - [gamma][delta] cells: a right time and a right place for a conserved third way of protection JO - Annu Rev Immunol VL - 18 UR - https://doi.org/10.1146/annurev.immunol.18.1.975 DO - 10.1146/annurev.immunol.18.1.975 ID - Hayday2000 ER - TY - JOUR AU - Begley, M. AU - Gahan, C. G. AU - Kollas, A. K. AU - Hintz, M. AU - Hill, C. AU - Jomaa, H. PY - 2004 DA - 2004// TI - The interplay between classical and alternative isoprenoid biosynthesis controls gammadelta T cell bioactivity of Listeria monocytogenes JO - FEBS Lett VL - 561 UR - https://doi.org/10.1016/S0014-5793(04)00131-0 DO - 10.1016/S0014-5793(04)00131-0 ID - Begley2004 ER - TY - JOUR AU - Eberl, M. AU - Hintz, M. AU - Reichenberg, A. AU - Kollas, A. K. AU - Wiesner, J. AU - Jomaa, H. PY - 2003 DA - 2003// TI - Microbial isoprenoid biosynthesis and human gammadelta T cell activation JO - FEBS Lett VL - 544 UR - https://doi.org/10.1016/S0014-5793(03)00483-6 DO - 10.1016/S0014-5793(03)00483-6 ID - Eberl2003 ER - TY - JOUR AU - Bukowski, J. F. AU - Morita, C. T. AU - Brenner, M. B. PY - 1999 DA - 1999// TI - Human gamma delta T cells recognize alkylamines derived from microbes, edible plants, and tea: implications for innate immunity JO - Immunity VL - 11 UR - https://doi.org/10.1016/S1074-7613(00)80081-3 DO - 10.1016/S1074-7613(00)80081-3 ID - Bukowski1999 ER - TY - JOUR AU - Gober, H. J. AU - Kistowska, M. AU - Angman, L. AU - Jeno, P. AU - Mori, L. AU - Libero, G. PY - 2003 DA - 2003// TI - Human T cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells JO - J Exp Med VL - 197 UR - https://doi.org/10.1084/jem.20021500 DO - 10.1084/jem.20021500 ID - Gober2003 ER - TY - JOUR AU - Thompson, K. AU - Rogers, M. J. PY - 2004 DA - 2004// TI - Statins prevent bisphosphonate-induced gamma, delta-T-cell proliferation and activation in vitro JO - J Bone Miner Res VL - 19 UR - https://doi.org/10.1359/JBMR.0301230 DO - 10.1359/JBMR.0301230 ID - Thompson2004 ER - TY - JOUR AU - Groh, V. AU - Steinle, A. AU - Bauer, S. AU - Spies, T. PY - 1998 DA - 1998// TI - Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells JO - Science VL - 279 UR - https://doi.org/10.1126/science.279.5357.1737 DO - 10.1126/science.279.5357.1737 ID - Groh1998 ER - TY - JOUR AU - Witherden, D. A. AU - Havran, W. L. PY - 2012 DA - 2012// TI - EPCR: a stress trigger for gammadelta T cells JO - Nat Immunol VL - 13 UR - https://doi.org/10.1038/ni.2398 DO - 10.1038/ni.2398 ID - Witherden2012 ER - TY - JOUR AU - Andreu-Ballester, J. C. AU - Garcia-Ballesteros, C. AU - Benet-Campos, C. AU - Amigo, V. AU - Almela-Quilis, A. AU - Mayans, J. PY - 2012 DA - 2012// TI - Values for alphabeta and gammadelta T-lymphocytes and CD4+, CD8+, and CD56+ subsets in healthy adult subjects: assessment by age and gender JO - Cytometry B Clin Cytom VL - 82 UR - https://doi.org/10.1002/cyto.b.21020 DO - 10.1002/cyto.b.21020 ID - Andreu-Ballester2012 ER - TY - JOUR AU - Michishita, Y. AU - Hirokawa, M. AU - Guo, Y. M. AU - Abe, Y. AU - Liu, J. AU - Ubukawa, K. PY - 2011 DA - 2011// TI - Age-associated alteration of gammadelta T-cell repertoire and different profiles of activation-induced death of Vdelta1 and Vdelta2 T cells JO - Int J Hematol VL - 94 UR - https://doi.org/10.1007/s12185-011-0907-7 DO - 10.1007/s12185-011-0907-7 ID - Michishita2011 ER - TY - JOUR AU - Dechanet, J. AU - Merville, P. AU - Lim, A. AU - Retiere, C. AU - Pitard, V. AU - Lafarge, X. PY - 1999 DA - 1999// TI - Implication of gammadelta T cells in the human immune response to cytomegalovirus JO - J Clin Invest VL - 103 UR - https://doi.org/10.1172/JCI5409 DO - 10.1172/JCI5409 ID - Dechanet1999 ER - TY - JOUR AU - Lafarge, X. AU - Merville, P. AU - Cazin, M. C. AU - Berge, F. AU - Potaux, L. AU - Moreau, J. F. PY - 2001 DA - 2001// TI - Cytomegalovirus infection in transplant recipients resolves when circulating gammadelta T lymphocytes expand, suggesting a protective antiviral role JO - J Infect Dis VL - 184 UR - https://doi.org/10.1086/322843 DO - 10.1086/322843 ID - Lafarge2001 ER - TY - JOUR AU - Knight, A. AU - Madrigal, A. J. AU - Grace, S. AU - Sivakumaran, J. AU - Kottaridis, P. AU - Mackinnon, S. PY - 2010 DA - 2010// TI - The role of Vdelta2-negative gammadelta T cells during cytomegalovirus reactivation in recipients of allogeneic stem cell transplantation JO - Blood VL - 116 UR - https://doi.org/10.1182/blood-2010-01-255166 DO - 10.1182/blood-2010-01-255166 ID - Knight2010 ER - TY - JOUR AU - Halary, F. AU - Pitard, V. AU - Dlubek, D. AU - Krzysiek, R. AU - Salle, H. AU - Merville, P. PY - 2005 DA - 2005// TI - Shared reactivity of V{delta}2(neg) {gamma}{delta} T cells against cytomegalovirus-infected cells and tumor intestinal epithelial cells JO - J Exp Med VL - 201 UR - https://doi.org/10.1084/jem.20041851 DO - 10.1084/jem.20041851 ID - Halary2005 ER - TY - JOUR AU - Pitard, V. AU - Roumanes, D. AU - Lafarge, X. AU - Couzi, L. AU - Garrigue, I. AU - Lafon, M. E. PY - 2008 DA - 2008// TI - Long-term expansion of effector/memory Vdelta2-gammadelta T cells is a specific blood signature of CMV infection JO - Blood VL - 112 UR - https://doi.org/10.1182/blood-2008-01-136713 DO - 10.1182/blood-2008-01-136713 ID - Pitard2008 ER - TY - JOUR AU - Couzi, L. AU - Pitard, V. AU - Sicard, X. AU - Garrigue, I. AU - Hawchar, O. AU - Merville, P. PY - 2012 DA - 2012// TI - Antibody-dependent anti-cytomegalovirus activity of human gammadelta T cells expressing CD16 (FcgammaRIIIa) JO - Blood VL - 119 UR - https://doi.org/10.1182/blood-2011-06-363655 DO - 10.1182/blood-2011-06-363655 ID - Couzi2012 ER - TY - JOUR AU - Willcox, C. R. AU - Pitard, V. AU - Netzer, S. AU - Couzi, L. AU - Salim, M. AU - Silberzahn, T. PY - 2012 DA - 2012// TI - Cytomegalovirus and tumor stress surveillance by binding of a human gammadelta T cell antigen receptor to endothelial protein C receptor JO - Nat Immunol VL - 13 UR - https://doi.org/10.1038/ni.2394 DO - 10.1038/ni.2394 ID - Willcox2012 ER - TY - JOUR AU - Roux, A. AU - Mourin, G. AU - Larsen, M. AU - Fastenackels, S. AU - Urrutia, A. AU - Gorochov, G. PY - 2013 DA - 2013// TI - Differential impact of age and cytomegalovirus infection on the gammadelta T cell compartment JO - J Immunol VL - 191 UR - https://doi.org/10.4049/jimmunol.1202940 DO - 10.4049/jimmunol.1202940 ID - Roux2013 ER - TY - JOUR AU - Wistuba-Hamprecht, K. AU - Frasca, D. AU - Blomberg, B. AU - Pawelec, G. AU - Derhovanessian, E. PY - 2013 DA - 2013// TI - Age-associated alterations in gammadelta T-cells are present predominantly in individuals infected with Cytomegalovirus JO - Immun Ageing VL - 10 UR - https://doi.org/10.1186/1742-4933-10-26 DO - 10.1186/1742-4933-10-26 ID - Wistuba-Hamprecht2013 ER - TY - JOUR AU - Couzi, L. AU - Pitard, V. AU - Moreau, J. F. AU - Merville, P. AU - Dechanet-Merville, J. PY - 2015 DA - 2015// TI - Direct and indirect effects of cytomegalovirus-induced gammadelta T cells after kidney transplantation JO - Front Immunol VL - 6 UR - https://doi.org/10.3389/fimmu.2015.00003 DO - 10.3389/fimmu.2015.00003 ID - Couzi2015 ER - TY - STD TI - Wistuba-Hamprecht K, Pawelec G, Derhovanessian E. OMIP-020: Phenotypic characterization of human gammadelta T-cells by multicolor flow cytometry. Cytometry A. 2014. ID - ref34 ER - TY - JOUR AU - Bertram, L. AU - Bockenhoff, A. AU - Demuth, I. AU - Duzel, S. AU - Eckardt, R. AU - Li, S. C. PY - 2014 DA - 2014// TI - Cohort profile: the Berlin aging study II (BASE-II) JO - Int J Epidemiol VL - 43 UR - https://doi.org/10.1093/ije/dyt018 DO - 10.1093/ije/dyt018 ID - Bertram2014 ER - TY - JOUR AU - Derhovanessian, E. AU - Maier, A. B. AU - Hahnel, K. AU - Zelba, H. AU - Craen, A. J. AU - Roelofs, H. PY - 2013 DA - 2013// TI - Lower proportion of naive peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people JO - Age (Dordr) VL - 35 UR - https://doi.org/10.1007/s11357-012-9425-7 DO - 10.1007/s11357-012-9425-7 ID - Derhovanessian2013 ER - TY - JOUR AU - Strindhall, J. AU - Nilsson, B. O. AU - Lofgren, S. AU - Ernerudh, J. AU - Pawelec, G. AU - Johansson, B. PY - 2007 DA - 2007// TI - No Immune Risk Profile among individuals who reach 100 years of age: findings from the Swedish NONA immune longitudinal study JO - Exp Gerontol VL - 42 UR - https://doi.org/10.1016/j.exger.2007.05.001 DO - 10.1016/j.exger.2007.05.001 ID - Strindhall2007 ER - TY - JOUR AU - Chien, Y. H. AU - Meyer, C. AU - Bonneville, M. PY - 2014 DA - 2014// TI - Gammadelta T cells: first line of defense and beyond JO - Annu Rev Immunol VL - 32 UR - https://doi.org/10.1146/annurev-immunol-032713-120216 DO - 10.1146/annurev-immunol-032713-120216 ID - Chien2014 ER - TY - JOUR AU - Argentati, K. AU - Re, F. AU - Donnini, A. AU - Tucci, M. G. AU - Franceschi, C. AU - Bartozzi, B. PY - 2002 DA - 2002// TI - Numerical and functional alterations of circulating gammadelta T lymphocytes in aged people and centenarians JO - J Leukoc Biol VL - 72 ID - Argentati2002 ER - TY - JOUR AU - Couzi, L. AU - Levaillant, Y. AU - Jamai, A. AU - Pitard, V. AU - Lassalle, R. AU - Martin, K. PY - 2010 DA - 2010// TI - Cytomegalovirus-induced gammadelta T cells associate with reduced cancer risk after kidney transplantation JO - J Am Soc Nephrol VL - 21 UR - https://doi.org/10.1681/ASN.2008101072 DO - 10.1681/ASN.2008101072 ID - Couzi2010 ER - TY - STD TI - Wistuba-Hamprecht K, Di Benedetto S, Schilling B, Sucker A, Schadendorf D, Garbe C, et al. Phenotypic characterization and prognostic impact of circulating gammadelta and alphabeta T-cells in metastatic malignant melanoma. Int J Cancer. 2015. ID - ref41 ER - TY - JOUR AU - Girardi, M. PY - 2006 DA - 2006// TI - Immunosurveillance and immunoregulation by gammadelta T cells JO - J Invest Dermatol VL - 126 UR - https://doi.org/10.1038/sj.jid.5700003 DO - 10.1038/sj.jid.5700003 ID - Girardi2006 ER - TY - JOUR AU - Bonneville, M. AU - Fournie, J. J. PY - 2005 DA - 2005// TI - Sensing cell stress and transformation through Vgamma9Vdelta2 T cell-mediated recognition of the isoprenoid pathway metabolites JO - Microbes Infect VL - 7 UR - https://doi.org/10.1016/j.micinf.2005.03.004 DO - 10.1016/j.micinf.2005.03.004 ID - Bonneville2005 ER - TY - JOUR AU - Argentati, K. AU - Re, F. AU - Serresi, S. AU - Tucci, M. G. AU - Bartozzi, B. AU - Bernardini, G. PY - 2003 DA - 2003// TI - Reduced number and impaired function of circulating gamma delta T cells in patients with cutaneous primary melanoma JO - J Invest Dermatol VL - 120 UR - https://doi.org/10.1046/j.1523-1747.2003.12141.x DO - 10.1046/j.1523-1747.2003.12141.x ID - Argentati2003 ER - TY - JOUR AU - Chidrawar, S. AU - Khan, N. AU - Wei, W. AU - McLarnon, A. AU - Smith, N. AU - Nayak, L. PY - 2009 DA - 2009// TI - Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals JO - Clin Exp Immunol VL - 155 UR - https://doi.org/10.1111/j.1365-2249.2008.03785.x DO - 10.1111/j.1365-2249.2008.03785.x ID - Chidrawar2009 ER - TY - JOUR AU - Derhovanessian, E. AU - Maier, A. B. AU - Beck, R. AU - Jahn, G. AU - Hahnel, K. AU - Slagboom, P. E. PY - 2010 DA - 2010// TI - Hallmark features of immunosenescence are absent in familial longevity JO - J Immunol VL - 185 UR - https://doi.org/10.4049/jimmunol.1001629 DO - 10.4049/jimmunol.1001629 ID - Derhovanessian2010 ER - TY - JOUR AU - Appay, V. AU - Rowland-Jones, S. L. PY - 2004 DA - 2004// TI - Lessons from the study of T-cell differentiation in persistent human virus infection JO - Semin Immunol VL - 16 UR - https://doi.org/10.1016/j.smim.2004.02.007 DO - 10.1016/j.smim.2004.02.007 ID - Appay2004 ER - TY - JOUR AU - Derhovanessian, E. AU - Maier, A. B. AU - Hahnel, K. AU - Beck, R. AU - Craen, A. J. AU - Slagboom, E. P. PY - 2011 DA - 2011// TI - Infection with cytomegalovirus but not herpes simplex virus induces the accumulation of late-differentiated CD4+ and CD8+ T-cells in humans JO - J Gen Virol VL - 92 UR - https://doi.org/10.1099/vir.0.036004-0 DO - 10.1099/vir.0.036004-0 ID - Derhovanessian2011 ER - TY - STD TI - Di Benedetto S, Derhovanessian E, Steinhagen-Thiessen E, Goldeck D, Muller L, Pawelec G. Impact of age, sex and CMV-infection on peripheral T cell phenotypes: results from the Berlin BASE-II Study. Biogerontology. 2015. ID - ref49 ER - TY - JOUR AU - Angelini, D. F. AU - Borsellino, G. AU - Poupot, M. AU - Diamantini, A. AU - Poupot, R. AU - Bernardi, G. PY - 2004 DA - 2004// TI - FcgammaRIII discriminates between 2 subsets of Vgamma9Vdelta2 effector cells with different responses and activation pathways JO - Blood VL - 104 UR - https://doi.org/10.1182/blood-2004-01-0331 DO - 10.1182/blood-2004-01-0331 ID - Angelini2004 ER - TY - JOUR AU - Arens, R. AU - Remmerswaal, E. B. AU - Bosch, J. A. AU - Lier, R. A. PY - 2015 DA - 2015// TI - 5(th) International Workshop on CMV and Immunosenescence - A shadow of cytomegalovirus infection on immunological memory JO - Eur J Immunol VL - 45 UR - https://doi.org/10.1002/eji.201570044 DO - 10.1002/eji.201570044 ID - Arens2015 ER -