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Table 1 Evaluation of the major T cell population

From: Fetal thymus graft enables recovery from age-related hearing loss and expansion of CD4-Positive T cells expressing IL-1 receptor type 2 and regulatory T Cells

Groups CD4+CD3+ (%) CD8+CD3+ (%)
C (untreated mice of 12 months old) 10.4 ± 0.08 3.85 ± 0.21
D (thymus-grafted mice of 12 months old) 12.9 ± 0.26* 3.86 ± 0.36a
  1. To evaluate the major T cell population, CD4+CD3+ T cells and CD8+CD3+ T cells were analyzed by flow cytometry after the staining with FITC-anti-mouse CD4 mAb plus PE-anti-mouse CD3 mAb, or FITC-anti-mouse CD8 mAb plus PE-anti-mouse CD3 mAb
  2. *The frequency of CD4+CD3+T cells in Group D was significantly higher than those in Group C (p < 0.002)
  3. aThere was no significant difference of the frequencies of CD8+ CD3+T cells between Groups C and D. All experiments were in triplicate n = 3/group (mean ± SD)