Skip to main content

Table 2 Down-regulation of IL-1R2 and FR4 on splenic CD4+ T cells by fetal thvmus graft

From: Fetal thymus graft enables recovery from age-related hearing loss and expansion of CD4-Positive T cells expressing IL-1 receptor type 2 and regulatory T Cells

Groups Square R1a Square R2 Square R3
  CD121a+ cells (%) CD121b cells (%) FR4 hi cells (%)
  on CD4+ cells* on CD4+ cells on CD4+ cells
A, 2 months old 0.46 ± 0.07 0.33 ± 0.08 11.02 ± 0.81
B, 6 months old 0.39 ± 0.14 0.83 ± 0.21** 23.52 ± 0.80****
C, 12 months old 0.46 ± 0.18 1.07 ± 0.13 22.10 ± 1.63
D, 12 months old 0.58 ± 0.28 0.57 ± 0.03*** 12.85 ± 0.54*****
Thymus-grafted    
  1. aSquares of R1-R3 are shown in Fig. 5
  2. * p > 0.05 between any groups
  3. ** p < 0005 between Groups A and B. p < 0.01 between Groups B and D. p > 0.05 between Groups B and C
  4. *** p < 0.005 between Groups A and D
  5. **** p < 0.005 between Groups A and B. p < 0.005 between Groups B and D. p > 0.05 between Groups B and C
  6. ***** p < 0.01 between Groups A and D. All experiments were run in triplicate n = 3–4/group (mean ± SD)