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Table 1 Clinical and biological characteristics of the study population

From: End stage renal disease patients have a skewed T cell receptor Vβ repertoire

  Healthy individuals ESRD Patients P value
Number of individuals 51 45  
Age (young/eldely) (years; mean ± SD) 33.1 ± 7.6/68.0 ± 3.0 32.9 ± 9.2 / 68.3 ± 3.5 NS/NSa
Sex (% male) 41.2 68.9 P < 0.05
CMV IgG serostatus (% pos) 52.9 51.1 NS
T cells number in peripheral blood (106/μl; mean ± SD) 1274 ± 304 1164 ± 260 NS
Renal replacement therapy (number; %)   44.4  
Duration of Renal replacement therapy (months; median/rang)   13/3-68  
 Hemodialysis (%)   80.0  
 Peritoneal dialysis (%)   15.0  
 Peritoneal dialysis followed hemodialysis (%)   5.0  
Underlying kidney disease    
 Nephrosclerosis/atherosclerosis/hypertensive nephropathy (%)   17.8  
 Primary glomerulopathy (%)   6.7  
 Diabetic nephropathy (%)   20.0  
 Reflux nephropathy (%)   17.8  
 Polycystic kidney disease (%)   20.0  
 Other (%)   15.6  
 Unknown (%)   2.2  
  1. Abbreviations: ESRD end stage renal disease, CMV cytomegalovirus, NS not significant
  2. aAge categories of young (≤45 years) and elderly ( ≥65 years) were used