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Table 2 The variables related to a skewed TCR Vβ repertoire

From: End stage renal disease patients have a skewed T cell receptor Vβ repertoire

  Non-skewed TCR Vβ Skewed TCR Vβ Odds ratio P value
Age (years, median) 41 65 3.1a < 0.05
% of CMV seropositivity 30.7 74.5 13.8b < 0.05
% of ESRD patients 28.6 70.0 10.2c < 0.05
% of patients on renal replacement therapy 35.8 48.4   NS
Underlying kidney disease (number)     
Nephrosclerosis/atherosclerosis/hypertensive nephropathy 1 7   NS
Primary glomerulopathy 0 3   NS
Diabetic nephropathy 2 7   NS
Reflux nephropathy 4 4   NS
Polycystic kidney disease 2 7   NS
Other 5 2   
Unknown 0 1   
  1. Abbreviations: TCR T cell receptor, NS not significant
  2. ameans the odds of a skewed TCR Vβ repertoire in elderly population is 3.1 times higher than in the young population
  3. bmeans the odds of a skewed TCR Vβ repertoire in CMV- IgG seropositive population is 13.8 times higher than in the CMV- IgG seronegative population
  4. Cmeans the odds of a skewed TCR Vβ repertoire in patients is 10.2 times higher than in the healthy individuals