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Fig. 5 | Immunity & Ageing

Fig. 5

From: Efforts of the human immune system to maintain the peripheral CD8+ T cell compartment after childhood thymectomy

Fig. 5

Proportions of CD31+ and CD103+ CD8+ T cells, Interleukin-7 (IL-7) concentrations, TRECs and relative telomere lengths in YATEC aged >30 years (YATEC > 30a) and YHC aged >30 years (YHC > 30a). Proportions of CD31+ (a) and CD103+ cells in CD8+ T cells (b) are shown in YATEC aged >30 years (YATEC > 30a) who had thymectomy more than 25 years ago compared to YHC aged >30 years (YHC > 30a). Significantly higher proportions of CD103+ CD8+ T cells (b) and a trend for higher IL-7 concentrations (c) were found in YATEC > 30a compared to YHC > 30a. Negative TRECs were seen in five YATEC > 30a compared to YHC > 30a with only one individual with negative TRECs (d). A trend to lower relative telomere lengths (RTLs) was demonstrated in YATEC > 30a compared to YHC > 30a (e). Horizontal lines indicate the median. A p ≤ 0.05 indicates statistical significance (Mann–Whitney U test)

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Immunity & Ageing

ISSN: 1742-4933

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