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Table 2 Spearman partial correlation coefficients (r)1 between total neopterin, pyridoxal 5'-phosphate (PLP) and markers of metabolic factors

From: Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study

 

PLP, μmol/L

Waist circumference, cm

Tryglicerides, mmol/L

High-density lipoprotein cholesterol, mmol/L

Systolic blood pressure (mmHg)

Diastolic blood pressure, mmHg

HbA1c (%)

hsCRP, mg/L

 

ρ

p

ρ

p

ρ

p

ρ

p

ρ

p

ρ

p

ρ

p

ρ

p

 

Men

Neopterin, nmol/L

−0.13

0.04

0.24

<0.01

−0.07

0.29

−0.18

0.01

0.09

0.22

0.16

0.04

0.01

0.91

0.18

0.01

PLP, μmol/L

  

0.08

0.24

−0.04

0.55

0.21

<0.01

−0.18

0.07

−0.05

0.57

−0.09

0.35

−0.11

0.11

Waist circumference, cm

    

0.26

<0.01

−0.23

<0.01

0.26

<0.01

0.28

<0.01

0.12

0.15

0.21

0.02

Tryglicerides, mmol/L

      

−0.35

<0.01

0.15

0.04

0.24

0.00

0.06

0.50

0.02

0.79

High-density lipoprotein cholesterol, mmol/L

        

−0.18

0.01

−0.17

0.02

0.04

0.58

−0.17

0.01

Systolic blood pressure, mmHg

          

0.66

<0.01

0.11

0.27

0.08

0.29

Diastolic blood pressure, mmHg

            

−0.01

0.89

0.07

0.36

HbA1c (%)

              

0.07

0.45

 

Women

Neopterin, nmol/L

−0.15

0.01

0.10

0.09

0.02

0.68

−0.24

<0.01

−0.05

0.43

−0.07

0.28

−0.11

0.23

0.15

0.01

PLP, μmol/L

  

−0.06

0.29

−0.08

0.17

0.14

0.02

−0.08

0.44

−0.03

0.78

0.25

0.01

−0.20

<0.01

Waist circumference, cm

    

0.31

<0.01

−0.28

<0.01

0.25

<0.01

0.21

<0.01

0.14

0.15

0.27

<0.01

Tryglicerides, mmol/L

      

−0.35

<0.01

0.16

0.01

0.13

0.03

0.07

0.50

0.15

0.12

High-density lipoprotein cholesterol, mmol/L

        

−0.04

0.48

0.01

0.89

0.14

0.12

−0.09

0.12

Systolic blood pressure, mmHg

          

0.64

<0.01

0.01

0.95

0.19

<0.01

Diastolic blood pressure, mmHg

            

0.03

0.76

0.04

0.56

HbA1c (%)

              

0.00

0.99

  1. 1.The partial correlation coefficients were adjusted for age at blood collection (years), sex, EPIC study centers, and smoking status (never, former, current, and unknown)
  2. Abbreviations: PLP pyridoxal 5'-phosphate, WC waist circumference, TG triglycerides, HDLC high-density lipoprotein cholesterol, SBP systolic blood pressure, DBP diastolic blood pressure, hsCRP high-sensitivity C-reactive protein, HbA1c glycatred hemoglobin