Table 5 Univariate analysis of C3a, C4a and C5a plasma levels in nAMD patients not responding, partially responding and completely responding to anti-VEGF Ab therapy
Variables (ng/ml) | Controls (mean ± SD) | Non responders (mean ± SD) | Partial responders (mean ± SD) | Complete responders (mean ± SD) | P value |
|---|---|---|---|---|---|
n = 43 | n = 4 | n = 48 | n = 44 | Partial vs complete respondersa | |
C3a | 11.95 ± 3.30 | 13.97 ± 3.94 | 15.61 ± 5.18 | 13.67 ± 3.45 | 0.041 |
C4a | 68.91 ± 33.23 | 79.97 ± 75.52 | 120.85 ± 98.30 | 97.57 ± 64.80 | 0.147 |
C5a | 8.34 ± 2.05 | 8.62 ± 2.47 | 9.31 ± 2.72 | 9.63 ± 2.80 | 0.654 |