Fig. 1

Circulating levels of molecules involved into endothelium remodeling in aortic dissection and controls patients. AAD patients have higher level of CD40L, MPO, TIMP-1, and MMP-1 than controls (p < 0.05). The same trend was also highlighted subdividing AAD patients in type A and B according to Stanford classification (p < 0.05). No statistically significance was observed in MMP-2 and MMP-9 circulating levels between AAD and control patients. Between A and B subgroups of ADD patients any statistically significance was observed (p = 0.05)