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Fig. 1 | Immunity & Ageing

Fig. 1

From: HCV monoinfection and HIV/HCV coinfection enhance T-cell immune senescence in injecting drug users early during infection

Fig. 1

Flowcytometric analysis of telomere length within T-cell subsets. a Representative histograms of CD8+ telomere length (blue) and calf thymocytes (green) at the baseline timepoint (t = 1) and a follow-up timepoint more than 15 years later (t = 2). b Telomere length analysis (or relative Telomere lengths) within T-cell subsets defined by CD27 and CD57-expression (left panel) as CD27 + CD57- (red), CD27-CD57- (green) and CD27-CD57+ (purple). c Differences in relative telomere length (RTL) in healthy donors between immature (CD27 + CD57-), mature (CD27-CD57-) and mature differentiated (CD27-CD57+) T cells stratified for CD4 (left panel) and CD8 T cells (right panel). The black lines represent median values. Statistical analyses were performed using Kruskal-Wallis and post hoc Mann-Whitney U test, a two sided p-value <0.05 was considered statistically significant

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