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Fig. 4 | Immunity & Ageing

Fig. 4

From: The insulin receptor substrate Chico regulates antibacterial immune function in Drosophila

Fig. 4

Melanization and phenoloxidase activity are elevated in chico mutants. a Melanization of the wound site is shown at 40x magnification 3 h after injection with non-pathogenic Escherichia coli (strain K12), pathogenic Photorhabdus luminescens (strain TT01) bacteria, or sterile PBS in 7-10 day old Drosophila melanogaster chico mutants and yellow white (yw) background control flies. b Phenoloxidase activity in the hemolymph plasma of chico mutant and yw control flies injected with PBS, E. coli (Ec), or P. luminescens (Pl) as measured by the optical density at 492 nm after incubation with L-Dopa. Values are shown as the mean of three independent experiments with error bars representing standard deviations. *P < 0.05 (unpaired two-tailed t-test, GraphPad Prism5 software)

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