Fig. 8

Determination of pro-inflammatory cytokines in sera of cURTI young patients. Panel a: IL-1β serum level measurement; panel b: TNF-α serum level measurement; panel c: IL-6 serum level measurement; panel d: IL-8 serum level measurement. Serum cytokines were assayed by flex set kit using a citofluorimetry (FACS Aria III) as described in material and methods. T0 = before treatment, T1 = after six months, T2 = after one year of treatment. Symbols indicate statistical analysis between samples performed by Student’s t-test (GraphPad Prism 5.0 software) and values with p < 0.05 were considered significantly