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Table 3 Intervention effects on leukocyte subpopulations and circulating inflammatory markers

From: Elastic band resistance training influences transforming growth factor-ß receptor I mRNA expression in peripheral mononuclear cells of institutionalised older adults: the Vienna Active Ageing Study (VAAS)

 

Baseline (n = 67)

3 months (n = 67)

6 months (n = 67)

P-value (time)

Leukocytes [x109 cells/L]

    

 CT (n = 26)

7.2 (4.9–10.3)**

7.2 (4.1–11.9)

7.1 (5.4–9.4)

0.440

 RT (n = 20)

5.6 (3.1–9.1)

6.0 (3.2–8.9)

6.0 (3.3–9.8)*

0.001

 RTS (n = 21)

7.0 (4.4–13.3)**

7.2 (4.5–11.7)**

7.1 (4.7–13.0)

0.586

Lymphocytes [cells/μl]

    

 CT (n = 26)

1985 (910–3510)

2090 (890–3980)

2250 (930–3540)

0.387

 RT (n = 20)

1675 (830–3330)

1765 (912–3190)

1720 (1010–3430)

0.651

 RTS (n = 21)

2255 (1460–4700)

2340 (1570–4680)

2190 (1640–4930)

0.810

Monocytes [cells/μl]

    

 CT (n = 26)

610 (72–950)

550 (300–780)

590 (400–910)

0.534

 RT (n = 20)

520 (260–790)

475 (250–960)

510 (250–880)

0.104

 RTS (n = 21)

585 (320–960)

490 (300–840)

545 (330–900)

0.404

Neutrophils [cells/μl]

    

 CT (n = 26)

4300 (2410–6630)**

4010 (1990–7420)

3910 (3110–5880)

0.247

 RT (n = 20)

2876 (1530–6800)

3390 (1720–5880)

3520 (1800–7330)*

0.011

 RTS (n = 21)

4030 (2430–9860)

3930 (1720–8730)

4290 (1664–8680)

0.368

Basophils [cells/μl]

    

 CT (n = 26)

40 (20–111)

30 (10–90)

30 (20–100)

0.027

 RT (n = 20)

35 (10–90)

30 (10–100)

30 (10–80)

0.878

 RTS (n = 21)

40 (10–90)

40 (10–90)

40 (10–80)

0.344

Eosinophils [cells/μl]

    

 CT (n = 26)

210 (36–448)

170 (80–470)

220 (90–330)

0.911

 RT (n = 20)

160 (10–690)

186 (40–530)

200 (80–570)

0.381

 RTS (n = 21)

248 (90–470)

195 (20–630)

260 (90–650)

0.137

hs-CRP [mg/L]

    

 CT (n = 26)

2.0 (0.5–4.8)

2.4 (0.2–5.5)

1.8 (0.3–8.5)

0.424

 RT (n = 20)

1.9 (0.3–7.6)

2.4 (0.5–7.7)

2.0 (0.6–9.6)

0.645

 RTS (n = 21)

1.8 (0.6–5.4)

2.1 (0.6–8.5)

1.6 (0.4–5.5)

0.135

TGF-β [μg/L]

    

 CT (n = 26)

36.0 (18.7–73.7)

39.8 (18.4–67.8)

40.8 (21.9–67.9)

0.953

 RT (n = 20)

31.5 (16.7–50.0)

34.5 (18.3–59.7)

34.6 (12.7–57.3)

0.075

 RTS (n = 21)

33.7 (21.0–51.2)

38.0 (22.9–50.5)

35.5 (22.1–52.1)

0.431

  1. Data are expressed as medians (min–max); Differences over the time course were detected using the Friedman test and if significant, followed by Bonferroni-corrected post-hoc analyses (* p < 0.05 vs. baseline within respective study group). Differences between groups were analysed by Kruskal Wallis test, followed by Bonferroni-corrected post-hoc analyses (** p < 0.05 vs. RT group within respective time point; significant differences are marked in bold)
  2. Abbreviations: CT cognitive training, RT resistance training, RTS resistance training plus supplement, hs-CRP high sensitive C-reactive protein, TGF-β transforming growth factor-β