Fig. 3

Radar graph representing the balance of subjects with high frequency of inflammatory (▄) or regulatory () cytokine-producing cells of innate and adaptive immunity. Graphs were constructed with each axis displaying the proportion of subjects with high frequency of cytokine-producing cells within a given leukocyte subset. The values of each axis can be joined to form the central polygon area that represents the general inflammatory/regulatory cytokine balance. Increasing or decreasing central polygon areas reflects either higher or lower contribution of inflammatory versus regulatory cytokine balance in each age group. Analysis of the radar chart axes highlights the contribution of distinct leukocyte subset for the overall cytokine balance. Age groups were categorized as: Newborn – 0 years (n = 12); Children – 6–10 years (n = 23); Adolescent – 11–20 years (n = 22); Adults – 21–50 (n = 80); Middle Aged – 51–60 (n = 22); Elderly – 61–85 (n = 22)