Fig. 4
Signature of high frequency of cytokine producing-cells from innate and adaptive immune compartments by individuals of different age groups. Age groups were characterized as: Newborn – 0 years (n = 12); Children – 6–10 years (n = 23); Adolescent – 11–20 years (n = 22); Adults – 21–50 (n = 80); Middle Aged – 51–60 (n = 22); Elderly – 61–85 (n = 22). Ascendant frequency of cytokine-producing cells from innate and adaptive immune compartments in each group was represented by bars. Red bars represent inflammatory-cytokine-producing cells and the blue bars represent regulatory-cytokine-producing cells. Dotted line represent the 50th percentile that was used as a cut-off to identify relevant differences