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Fig. 1 | Immunity & Ageing

Fig. 1

From: Low expression of CD39 and CD73 genes in centenarians compared with octogenarians

Fig. 1

Effect of ageing on CD39 and CD73 gene expression in human peripheral blood cells. Quantification of CD39 (a) and CD73 (b) mRNA fold change in cells of young, middle-aged and older adults as well as centenarians. Gene expression level data for each gene and sample were normalized to ACTB signal (internal control) and relative to the mean normalized value of CD39/CD73 gene expression in young adults group. Error bars represent S.E.M. of the means obtained in each group (n = 13 per young adults and centenarians; n = 12 per middle-aged adults and n = 11 per older adults group). a: *** indicates statistically significant differences (p < 0.001) between older adults and the rest of groups. b: **** denotes highly significant differences (p < 0.0001) between older adults and the rest of groups; # # and # # # mean significant differences (p < 0.01 and p < 0.001, respectively) between groups linked by horizontal square brackets. The p values were determined by Mann–Whitney test

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