Fig. 10
From: pERK-dependent defective TCR-mediated activation of CD4+ T cells in end-stage renal disease patients
DUSP6 and DUSP1 expression in CD4+ T cell subsets from healthy individuals (HI) and end stage renal disease (ESRD) patients. DUSP6 expression in (a) total, (b) naive and (c) memory CD4+ T cells; (d) Differentiation-associated DUSP6 expression in CD4+ T cells; DUSP1 expression in (e) total, (f) naive and (g) memory CD4+ T cells; Dots and squares represent young (n = 4) and elderly HI (n = 6), and upward- and downward-facing triangles correspond to young (n = 4) and elderly (n = 5) patients, respectively. P value: *< 0.05; **< 0.01; ***< 0.001; Data are given as (individual values and) medians with interquartile ranges