Fig. 5
From: pERK-dependent defective TCR-mediated activation of CD4+ T cells in end-stage renal disease patients
Phosphorylation of p38 according to T cell differentiation status in healthy individuals (HI) and end stage renal disease (ESRD) patients. Phosphorylation of ERK in CD4+ T cells from (a) young HI (n = 13), (b) elderly HI (n = 11), (c) young patients (n = 12), and (d) elderly patients (n = 12), as well as CD8+ T cells from (e) young HI, (f) elderly HI, (g) young patients, and (h) elderly patients. Dots, squares, upward- and downward-facing triangles represent naive, central memory (CM), effector memory (EM) and highly differentiated effector T cells (EMRA) T cells, respectively. P value: *< 0.05; **< 0.01; ***< 0.001; Data are given as median with interquartile range