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Table 5 GMT before and 4 weeks after vaccination according to the frailty criteria

From: Influenza vaccine response in community-dwelling German prefrail and frail individuals

  

Frailty criteria

  

Weight loss

Low grip strength

Exhaustion

Low walking speed

Low physical activity

Vaccine strain

 

Yes (n = 10)

No (n = 63)

Yes (n = 39)

No (n = 34)

Yes (n = 55)

No (n = 18)

Yes (n = 37)

No (n = 36)

Yes (n = 17)

No (n = 56)

A/California/7/2009 (H1N1)

Before

16.2

25.5

23.9

24.0

21.8

31.7

23.7

24.2

20.0

25.3

After

121.3

83.6a

93.9

81.6

81.0

113.1

72.8

106.8b

90.4

87.2

A/Texas/50/2012 (H3N2)

Before

30.3

40.4

42.2

35.4

41.0

33.0

41.5

36.3

38.4

39.0

After

65.0

94.4

93.9

85.0

98.0

68.6

110.0

72.7c

55.4

103.7e

B/Massachusetts/2/2012

Before

6.6

9.6

8.8

9.4

9.9

7.1

9.6

8.6

9.2

9.1

After

18.7

18.3

17.3

19.6

20.5

13.1

24.1

13.9d

13.9

20.0f

  1. Data are geometric mean HAI titers (GMT). “Before” refers to baseline samples (i.e. 4 weeks before vaccination) and “after” refers to 4 weeks after vaccination. P values for difference in GMT between the subjects positive or negative for the individual frailty criteria: a p = 0.02; b p = 0.07; c p = 0.03; d p = 0.01; e p = 0.001; f p = 0.06