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Table 2 T cell and B cell subsets in CMV-negative and CMV-positive individuals

From: Long-term maintenance of diphtheria-specific antibodies after booster vaccination is hampered by latent infection with Cytomegalovirus

  CVM-negative CMV-positive p
mean ± SD mean ± SD  
CD4+ naïve 63.0 ± 12.4 52.0 ± 15.5 0.029*
central memory 36.2 ± 12.5 38.5 ± 15.3 0.605
effector memory 0.6 ± 0.4 5.3 ± 4.2 <0.0001**
TEMRA 0.7 ± 0.6 4.7 ± 5.2 <0.0001**
CD8+ naïve 42.2 ± 16.2 28.9 ± 15.4 0.024*
central memory 25.4 ± 9.7 17.9 ± 14.0 0.005**
effector memory 8.9 ± 8.8 8.4 ± 7.3 0.939
TEMRA 24.5 ± 16.7 45.7 ± 17.5 0.001**
B cells IgM+ 19.5 ± 8.6 16.8 ± 5.6 0.286
IgD+ 67.7 ± 11.9 64.6 ± 12.5 0.564
IgG+ 11.2 ± 8.0 11.4 ± 4.4 0.323
memory IgG 8.3 ± 6.1 8.4 ± 3.6 0.485
exhausted 9.4 ± 2.6 11.2 ± 6.8 0.862
  1. Percentage of naïve (CD45ROCD28+), central memory (CD45RO+CD28+), effector memory: (CD45RO+CD28), and TEMRA (CD45ROCD28) cells within CD3+CD4+ or CD3+CD8+ cells, respectively and of IgM+, IgD+, IgG+, memory IgG (CD27+IgG+, and exhausted (IgDCD27) B cells within CD20+ cells. Shown are mean values and standard deviation (SD) from 19 CMV-negative and 18 CMV-positive individuals. Differences between CMV-negative and CMV-positive groups were calculated by Mann-Whitney-U test. *p < 0.05; **p < 0.01