| Healthy controls (n = 28) | Patients with neovascular AMD (n = 29) | P-value |
---|---|---|---|
Demographics | |||
 Age, years, mean (SD) | 77.2 (6.6) | 79.4 (6.1) | 0.192 |
 Females, n (%) | 12 (43) | 20 (69) | 0.047 |
Co-morbidities | Â | Â | Â |
 Hypertension, n (%) | 13 (46) | 14 (48) | 0.889 |
 Hypercholesterolemia, n (%) | 9 (32) | 10 (34) | 0.851 |
 Cardiovascular diseases, n (%) | 12 (43) | 10 (34) | 0.516 |
 Type 2 diabetes, n (%) | 2 (7) | 2 (7) | 1.000 |
Lifestyle factors | |||
 Body mass index, mean (SD) | 25.8 (4.7) | 26.7 (5.2) | 0.506 |
 Physically active, n (%) | 6 (21) | 9 (31) | 0.410 |
 Alcohol consumption, median (IQR) | 7 (2 to 10) | 3 (1 to 9) | 0.126 |
 Smoking status, n (%) |  |  | 0.889 |
  Previous smoker | 15 (54) | 15 (52) |  |
  Non-smoker | 13 (46) | 14 (48) |  |
Blood measures | |||
 C-reactive protein, mg/L |  |  | 0.029 |
   < 2.9 mg/L | 23 (82) | 16 (55) |  |
  2.9–14.9 mg/L | 5 (18) | 13 (45) |  |
 White blood cell count, 109 cells/L, mean (SD) | 5.9 (1.2) | 6.4 (1.6) | 0.212 |
 Lymphocytes, mean (SD) | |||
  % | 29 (8) | 28 (9) | 0.892 |
  109 cells/L | 1.7 (0.5) | 1.8 (0.6) | 0.654 |
 Monocytes, mean (SD) | |||
  % | 7 (2) | 6 (3) | 0.457 |
  109 cells/L | 0.4 (0.1) | 0.4 (0.2) | 0.678 |
 Neutrophils, mean (SD) | |||
  % | 64 (8) | 65 (11) | 0.618 |
  109 cells/L | 3.8 (1.0) | 4.3 (1.5) | 0.198 |
 Neutrophils-to-lymphocytes, mean (SD) | 2.52 (1.03) | 2.80 (1.51) | 0.422 |