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Table 1 Participant characteristics

From: Altered activation state of circulating neutrophils in patients with neovascular age-related macular degeneration

  Healthy controls (n = 28) Patients with neovascular AMD (n = 29) P-value
Demographics
 Age, years, mean (SD) 77.2 (6.6) 79.4 (6.1) 0.192
 Females, n (%) 12 (43) 20 (69) 0.047
Co-morbidities    
 Hypertension, n (%) 13 (46) 14 (48) 0.889
 Hypercholesterolemia, n (%) 9 (32) 10 (34) 0.851
 Cardiovascular diseases, n (%) 12 (43) 10 (34) 0.516
 Type 2 diabetes, n (%) 2 (7) 2 (7) 1.000
Lifestyle factors
 Body mass index, mean (SD) 25.8 (4.7) 26.7 (5.2) 0.506
 Physically active, n (%) 6 (21) 9 (31) 0.410
 Alcohol consumption, median (IQR) 7 (2 to 10) 3 (1 to 9) 0.126
 Smoking status, n (%)    0.889
  Previous smoker 15 (54) 15 (52)  
  Non-smoker 13 (46) 14 (48)  
Blood measures
 C-reactive protein, mg/L    0.029
   < 2.9 mg/L 23 (82) 16 (55)  
  2.9–14.9 mg/L 5 (18) 13 (45)  
 White blood cell count, 109 cells/L, mean (SD) 5.9 (1.2) 6.4 (1.6) 0.212
 Lymphocytes, mean (SD)
  % 29 (8) 28 (9) 0.892
  109 cells/L 1.7 (0.5) 1.8 (0.6) 0.654
 Monocytes, mean (SD)
  % 7 (2) 6 (3) 0.457
  109 cells/L 0.4 (0.1) 0.4 (0.2) 0.678
 Neutrophils, mean (SD)
  % 64 (8) 65 (11) 0.618
  109 cells/L 3.8 (1.0) 4.3 (1.5) 0.198
 Neutrophils-to-lymphocytes, mean (SD) 2.52 (1.03) 2.80 (1.51) 0.422
  1. Parametric continuous variables are presented using mean and standard deviation (SD) and tested using the independent samples t-test. Non-parametric continuous variables are presented using median and interquartile range (IQR) and tested using the Mann-Whitney U test. Categorical variables are presented using numbers (n) and percentages (%) and tested using the χ2-test, but due to very small numbers is co-morbidity of type 2 diabetes tested using the Fisher’s Exact test