Skip to main content

Table 1 Participant characteristics

From: Altered activation state of circulating neutrophils in patients with neovascular age-related macular degeneration

 

Healthy controls (n = 28)

Patients with neovascular AMD (n = 29)

P-value

Demographics

 Age, years, mean (SD)

77.2 (6.6)

79.4 (6.1)

0.192

 Females, n (%)

12 (43)

20 (69)

0.047

Co-morbidities

   

 Hypertension, n (%)

13 (46)

14 (48)

0.889

 Hypercholesterolemia, n (%)

9 (32)

10 (34)

0.851

 Cardiovascular diseases, n (%)

12 (43)

10 (34)

0.516

 Type 2 diabetes, n (%)

2 (7)

2 (7)

1.000

Lifestyle factors

 Body mass index, mean (SD)

25.8 (4.7)

26.7 (5.2)

0.506

 Physically active, n (%)

6 (21)

9 (31)

0.410

 Alcohol consumption, median (IQR)

7 (2 to 10)

3 (1 to 9)

0.126

 Smoking status, n (%)

  

0.889

  Previous smoker

15 (54)

15 (52)

 

  Non-smoker

13 (46)

14 (48)

 

Blood measures

 C-reactive protein, mg/L

  

0.029

   < 2.9 mg/L

23 (82)

16 (55)

 

  2.9–14.9 mg/L

5 (18)

13 (45)

 

 White blood cell count, 109 cells/L, mean (SD)

5.9 (1.2)

6.4 (1.6)

0.212

 Lymphocytes, mean (SD)

  %

29 (8)

28 (9)

0.892

  109 cells/L

1.7 (0.5)

1.8 (0.6)

0.654

 Monocytes, mean (SD)

  %

7 (2)

6 (3)

0.457

  109 cells/L

0.4 (0.1)

0.4 (0.2)

0.678

 Neutrophils, mean (SD)

  %

64 (8)

65 (11)

0.618

  109 cells/L

3.8 (1.0)

4.3 (1.5)

0.198

 Neutrophils-to-lymphocytes, mean (SD)

2.52 (1.03)

2.80 (1.51)

0.422

  1. Parametric continuous variables are presented using mean and standard deviation (SD) and tested using the independent samples t-test. Non-parametric continuous variables are presented using median and interquartile range (IQR) and tested using the Mann-Whitney U test. Categorical variables are presented using numbers (n) and percentages (%) and tested using the χ2-test, but due to very small numbers is co-morbidity of type 2 diabetes tested using the Fisher’s Exact test