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Table 2 Blood biochemistry, CD4/8 cell ratio and PBL telomere length in study participants

From: Immunosenescence in persons with spinal cord injury in relation to urinary tract infections -a cross-sectional study-

  yCtr (IQR) ySCI (IQR) oCtr (IQR) oSCI (IQR) yCtr-oCtr (p-value) ySCI-oSCI (p-value) yCtr-ySCI (p-value) oCtr-oSCI (p-value)
Total prot. (mg/ml) 71.0 (4) 66.5 (7) 70.0 (5) 68.0 (7) 0.06 ↓ 0.16 ↔ <.001 0.30
pIgG (mg/ml) 10.7 (4) 9.8 (3) 10.2 (4) 9.7 (4) 0.28 ↔ 0.85 ↔ 0.30 0.82
IL-2 (pg/ml) 5.5 (3) 6.2 (5) 6.0 (2) 6.1 (2) 0.12 ↔ 0.27 ↔ <.01 0.70
IL-4 (pg/ml) 1.5 (0.6) 1.3 (0.2) 2.0 (1.1) 1.4 (0.5) <.01 ↑ 0.14 ↔ <.01 <.001
IL-10 (pg/ml) 3.6 (3) 2.9 (3) 5.0 (4) 3.9 (3) <.05 ↑ 0.12 ↔ 0.25 0.19
G-CSF (pg/ml) 26.3 (7) 25.0 (5) 31.0 (10) 26.9 (7) <.05 ↑ <.05 ↑ <.05 0.05
GM-CSF (pg/ml) 67 (25) 97 (50) 71 (30) 72 (35) 0.14 ↔ <.01 ↓ <.001 0.44
MCP-1 (pg/ml) 138 (28) 131 (20) 153 (43) 134 (27) <.05 ↑ 0.29 ↔ 0.10 <.01
CD4/8 (ratio) 2.4 (1.4) 2.1 (2.2) 3.0 (2.7) 2.9 (2.7) <.05 ↑ 0.08 ↑ 0.69 0.71
Telomere length PBL (Norm. to yCtr) 1 (0.5) 1.0 (0.4) 0.8 (0.3) 0.9 (0.3) <.05 ↓ 0.09↓ 0.44 0.07
  1. Median values are shown
  2. IQR inter quartile range is shown in brackets, N/A not applicable, SCI spinal cord injury, PBL peripheral blood leucocyte, ↑ ↓↔ increasing, decreasing or no trend (p > 0.1) with age