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Table 2 Blood biochemistry, CD4/8 cell ratio and PBL telomere length in study participants

From: Immunosenescence in persons with spinal cord injury in relation to urinary tract infections -a cross-sectional study-

 

yCtr (IQR)

ySCI (IQR)

oCtr (IQR)

oSCI (IQR)

yCtr-oCtr (p-value)

ySCI-oSCI (p-value)

yCtr-ySCI (p-value)

oCtr-oSCI (p-value)

Total prot. (mg/ml)

71.0 (4)

66.5 (7)

70.0 (5)

68.0 (7)

0.06 ↓

0.16 ↔

<.001

0.30

pIgG (mg/ml)

10.7 (4)

9.8 (3)

10.2 (4)

9.7 (4)

0.28 ↔

0.85 ↔

0.30

0.82

IL-2 (pg/ml)

5.5 (3)

6.2 (5)

6.0 (2)

6.1 (2)

0.12 ↔

0.27 ↔

<.01

0.70

IL-4 (pg/ml)

1.5 (0.6)

1.3 (0.2)

2.0 (1.1)

1.4 (0.5)

<.01 ↑

0.14 ↔

<.01

<.001

IL-10 (pg/ml)

3.6 (3)

2.9 (3)

5.0 (4)

3.9 (3)

<.05 ↑

0.12 ↔

0.25

0.19

G-CSF (pg/ml)

26.3 (7)

25.0 (5)

31.0 (10)

26.9 (7)

<.05 ↑

<.05 ↑

<.05

0.05

GM-CSF (pg/ml)

67 (25)

97 (50)

71 (30)

72 (35)

0.14 ↔

<.01 ↓

<.001

0.44

MCP-1 (pg/ml)

138 (28)

131 (20)

153 (43)

134 (27)

<.05 ↑

0.29 ↔

0.10

<.01

CD4/8 (ratio)

2.4 (1.4)

2.1 (2.2)

3.0 (2.7)

2.9 (2.7)

<.05 ↑

0.08 ↑

0.69

0.71

Telomere length PBL (Norm. to yCtr)

1 (0.5)

1.0 (0.4)

0.8 (0.3)

0.9 (0.3)

<.05 ↓

0.09↓

0.44

0.07

  1. Median values are shown
  2. IQR inter quartile range is shown in brackets, N/A not applicable, SCI spinal cord injury, PBL peripheral blood leucocyte, ↑ ↓↔ increasing, decreasing or no trend (p > 0.1) with age