United Nations. World population prospects. 2017. http://esa.un.org/unpd/wpp. Accessed 30 July 2017.
Janssens JP. Pneumonia in the elderly (geriatric) population. Curr Opin Pulm Med. 2005;11:226–30.
PubMed
Google Scholar
Attal N, Deback C, Gavazzi G, Gorwood P, Labetoulle M, Liard F, et al. Functional decline and herpes zoster in older people: an interplay of multiple factors. Aging Clin Exp Res. 2015;27:757–65.
Article
Google Scholar
European Centre for Disease Prevention and Control: Vaccine schedule. 2017. http://vaccine-schedule.ecdc.europa.eu/Pages/Scheduler.aspx. Accessed 31 Oct 2017.
Kim DK, Riley LE, Harriman KH, Hunter P, Bridges CB. Advisory Commitee on immunization practices recommended immunization schedule for adults aged 19 years or older-United States, 2017. MMWR Morb Mortal Wkly Rep. 2017;66:136–8.
Article
PubMed
PubMed Central
Google Scholar
Thompson WW, Shay DK, Weintraub E, Brammer L, Cox N, Anderson LJ, et al. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA. 2003;289:179–86.
Article
PubMed
Google Scholar
Thompson WW, Shay DK, Weintraub E, Brammer L, Bridges CB, Cox NJ, et al. Influenza-associated hospitalizations in the United States. JAMA. 2004;292:1333–40.
Article
CAS
PubMed
Google Scholar
Shaw MW, Xu X, Li Y, Normand S, Ueki RT, Kunimoto GY, et al. Reappearance and global spread of variants of influenza B/Victoria/2/87 lineage viruses in the 2000-2001 and 2001-2002 seasons. Virology. 2002;303:1–8.
Article
CAS
PubMed
Google Scholar
Trucchi C, Alicino C, Orsi A, Paganino C, Barberis I, Grammatico F, et al. Fifteen years of epidemiologic, virologic and syndromic influenza surveillance: a focus on type B virus and the effects of vaccine mismatch in Liguria region, Italy. Hum Vaccin Immunother. 2017;13:456–63.
Article
PubMed
Google Scholar
Goodwin K, Viboud C, Simonsen L. Antibody response to influenza vaccination in the elderly: a quantitative review. Vaccine. 2006;24:1159–69.
Article
CAS
PubMed
Google Scholar
Mysliwska J, Trzonkowski P, Szmit E, Brydak LB, Machala M, Mysliwski A. Immunomodulating effect of influenza vaccination in the elderly differing in health status. Exp Gerontol. 2004;39:1447–58.
Article
CAS
PubMed
Google Scholar
Yao X, Hamilton RG, Weng NP, Xue QL, Bream JH, Li H, et al. Frailty is associated with impairment of vaccine-induced antibody response and increase in post-vaccination influenza infection in community-dwelling older adults. Vaccine. 2011;29:5015–21.
Article
PubMed
PubMed Central
Google Scholar
Osterholm MT, Kelley NS, Sommer A, Belongia EA. Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis. Lancet Infect Dis. 2012;12:36–44.
Article
PubMed
Google Scholar
Beyer WE, McElhaney J, Smith DJ, Monto AS, Nguyen-Van-Tam JS, Osterhaus AD. Cochrane re-arranged: support for policies to vaccinate elderly people against influenza. Vaccine. 2013;31:6030–3.
Article
PubMed
Google Scholar
De Donato S, Granoff D, Minutello M, Lecchi G, Faccini M, Agnello M, et al. Safety and immunogenicity of MF59-adjuvanted influenza vaccine in the elderly. Vaccine. 1999;17:3094–101.
Article
CAS
PubMed
Google Scholar
DiazGranados CA, Dunning AJ, Kimmel M, Kirby D, Treanor J, Collins A, et al. Efficacy of high-dose versus standard-dose influenza vaccine in older adults. N Engl J Med. 2014;371:635–45.
Article
PubMed
Google Scholar
Holland D, Booy R, de Looze F, Eizenberg P, McDonald J, Karrasch J, et al. Intradermal influenza vaccine administered using a new microinjection system produces superior immunogenicity in elderly adults: a randomized controlled trial. J Infect Dis. 2008;198:650–8.
Article
PubMed
Google Scholar
DelGiudice G, Hilbert AK, Bugarini R, Minutello A, Popova O, Toneatto D, et al. An MF59-adjuvanted inactivated influenza vaccine containing a/Panama/1999 (H3N2) induced broader serological protection against heterovariant influenza virus strain a/Fujian/2002 than a subunit and a split influenza vaccine. Vaccine. 2006;24:3063–5.
Article
CAS
Google Scholar
Ansaldi F, Bacilieri S, Durando P, Sticchi L, Valle L, Montomoli E, et al. Cross-protection by MF59-adjuvanted influenza vaccine: neutralizing and haemagglutination-inhibiting antibody activity against a(H3N2) drifted influenza viruses. Vaccine. 2008;26:1525–9.
Article
CAS
PubMed
Google Scholar
Mannino S, Villa M, Apolone G, Weiss NS, Groth N, Aquino I, et al. Effectiveness of adjuvanted influenza vaccination in elderly subjects in northern Italy. Am J Epidemiol. 2012;176:527–33.
Article
PubMed
PubMed Central
Google Scholar
Iob A, Brianti G, Zamparo E, Gallo T. Evidence of increased clinical protection of an MF59-adjuvant influenza vaccine compared to a non-adjuvant vaccine among elderly residents of long-term care facilities in Italy. Epidemiol Infect. 2005;133:687–93.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kyaw MH, Christie P, Clarke SC, Mooney JD, Ahmed S, Jones IG, et al. Invasive pneumococcal disease in Scotland, 1999-2001: use of record linkage to explore associations between patients and disease in relation to future vaccination policy. Clin Infect Dis. 2003;37:1283–91.
Article
PubMed
Google Scholar
Melegaro A, Edmunds WJ, Pebody R, Miller E, George R. The current burden of pneumococcal disease in England and Wales. J Inf Secur. 2006;52:37–48.
CAS
Google Scholar
Centers for Disease Control and Prevention. Prevention of pneumococcal disease: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 1997;46:1-24.
Bonten MJ, Huijts SM, Bolkenbaas M, Webber C, Patterson S, Gault S, et al. Polysaccharide conjugate vaccine against pneumococcal pneumonia in adults. N Engl J Med. 2015;372:1114–25.
Article
CAS
PubMed
Google Scholar
Dagan R. Serotype replacement in perspective. Vaccine. 2009;27(Suppl 3):C22–4.
Article
CAS
PubMed
Google Scholar
Hanquet G, Kissling E, Fenoll A, George R, Lepoutre A, Lernout T, et al. Pneumococcal serotypes in children in 4 European countries. Emerg Infect Dis. 2010;16:1428–39.
Article
PubMed
PubMed Central
Google Scholar
Elberse KE, van der Heide HG, Witteveen S, van de Pol I, Schot CS, van der Ende A, et al. Changes in the composition of the pneumococcal population and in IPD incidence in The Netherlands after the implementation of the 7-valent pneumococcal conjugate vaccine. Vaccine. 2012;30:7644–51.
Article
PubMed
Google Scholar
Esposito S, Principi N. Direct and indirect effects of the 13-valent pneumococcal conjugate vaccine administered to infants and young children. Future Microbiol. 2015;10:1599–607.
Article
CAS
PubMed
Google Scholar
Waight PA, Andrews NJ, Ladhani SN, Sheppard CL, Slack MP, Miller E. Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: an observational cohort study. Lancet Infect Dis. 2015;15:535–43.
Article
PubMed
Google Scholar
Regev-Yochay G, Katzir M, Strahilevitz J, Rahav G, Finn T, Miron D, et al. The herd effects of infant PCV7/PCV13 sequential implementation on adult invasive pneumococcal disease, six years post implementation; a nationwide study in Israel. Vaccine. 2017;35:2449–56.
Article
PubMed
Google Scholar
Oxman MN. Herpes zoster pathogenesis and cell-mediated immunity and immunosenescence. J Am Osteopath Assoc. 2009;109:S13–7.
PubMed
Google Scholar
Schmader K. Herpes zoster in older adults. Clin Infect Dis. 2001;32:1481–6.
Article
CAS
PubMed
Google Scholar
Pinchinat S, Cebrian-Cuenca AM, Bricout H, Johnson RW. Similar herpes zoster incidence across Europe: results from a systematic literature review. BMC Infect Dis. 13:2013, 170.
Mallick-Searle T, Snodgrass B, Brant JM. Postherpetic neuralgia: epidemiology, pathophysiology, and pain management pharmacology. J Multidiscip Healthc. 2016;9:447–54.
Article
PubMed
PubMed Central
Google Scholar
Schmader K, Gnann JW Jr, Watson CP. The epidemiological, clinical, and pathological rationale for the herpes zoster vaccine. J Infect Dis. 2008;197(Suppl 2):S207–15. S207-S215
Article
PubMed
Google Scholar
Scott FT, Johnson RW, Leedham-Green M, Davies E, Edmunds WJ, Breuer J. The burden of herpes zoster: a prospective population based study. Vaccine. 2006;24:1308–14.
Article
PubMed
Google Scholar
Levin MJ, Oxman MN, Zhang JH, Johnson GR, Stanley H, Hayward AR, et al. Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccine. J Infect Dis. 2008;197:825–35.
Article
CAS
PubMed
PubMed Central
Google Scholar
Oxman MN, Levin MJ, Johnson GR, Schmader KE, Straus SE, Gelb LD, et al. A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults. N Engl J Med. 2005;352:2271–84.
Article
CAS
PubMed
Google Scholar
Schmader KE, Oxman MN, Levin MJ, Johnson G, Zhang JH, Betts R, et al. Persistence of the efficacy of zoster vaccine in the shingles prevention study and the short-term persistence substudy. Clin Infect Dis. 2012;55:1320–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Morrison VA, Johnson GR, Schmader KE, Levin MJ, Zhang JH, Looney DJ, et al. Long-term persistence of zoster vaccine efficacy. Clin Infect Dis. 2015;60:900–9.
Article
PubMed
Google Scholar
Levin MJ, Schmader KE, Pang L, Williams-Diaz A, Zerbe G, Canniff J, et al. Cellular and Humoral responses to a second dose of herpes zoster vaccine administered 10 years after the first dose among older adults. J Infect Dis. 2016;213:14–22.
Article
PubMed
Google Scholar
Bayas JM, Vilella A, Bertran MJ, Vidal J, Batalla J, Asenjo MA, et al. Immunogenicity and reactogenicity of the adult tetanus-diphtheria vaccine. How many doses are necessary? Epidemiol Infect. 2001;127:451–60.
CAS
PubMed
PubMed Central
Google Scholar
Steger MM, Maczek C, Berger P, Grubeck-Loebenstein B, et al. Lancet. 1996;348:762.
Article
CAS
PubMed
Google Scholar
Van Damme P, Burgess M. Immunogenicity of a combined diphtheria-tetanus-acellular pertussis vaccine in adults. Vaccine. 2004;22:305–8.
Article
CAS
PubMed
Google Scholar
Kaml M, Weiskirchner I, Keller M, Luft T, Hoster E, Hasford J, et al. Booster vaccination in the elderly: their success depends on the vaccine type applied earlier in life as well as on pre-vaccination antibody titers. Vaccine. 2006;24:6808–11.
Article
CAS
PubMed
Google Scholar
Launay O, Toneatti C, Bernede C, Njamkepo E, Petitprez K, Leblond A, et al. Antibodies to tetanus, diphtheria and pertussis among healthy adults vaccinated according to the French vaccination recommendations. Hum Vaccin. 2009;5:341–6.
Article
PubMed
Google Scholar
Weinberger B, Schirmer M, Matteucci GR, Siebert U, Fuchs D, Grubeck-Loebenstein B. Recall responses to tetanus and diphtheria vaccination are frequently insufficient in elderly persons. PLoS One. 2013;8:e82967.
Article
PubMed
PubMed Central
Google Scholar
Grasse M, Meryk A, Schirmer M, Grubeck-Loebenstein B, Weinberger B. Booster vaccination against tetanus and diphtheria: insufficient protection against diphtheria in young and elderly adults. Immun Ageing. 2016;13:26.
Article
PubMed
PubMed Central
Google Scholar
Weinberger B. Adult vaccination against tetanus and diphtheria: the European perspective. Clin Exp Immunol. 2017;187:93–9.
Article
CAS
PubMed
Google Scholar
Weinberger B, Keller M, Fischer KH, Stiasny K, Neuner C, Heinz FX, et al. Decreased antibody titers and booster responses in tick-borne encephalitis vaccinees aged 50-90 years. Vaccine. 2010;28:3511–5.
Article
CAS
PubMed
Google Scholar
Stiasny K, Aberle JH, Keller M, Grubeck-Loebenstein B, Heinz FX. Age affects quantity but not quality of antibody responses after vaccination with an inactivated flavivirus vaccine against tick-borne encephalitis. PLoS One. 2012;7:e34145.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rendi-Wagner P, Tobias J, Moerman L, Goren S, Bassal R, Green M, et al. The seroepidemiology of Bordetella pertussis in Israel--estimate of incidence of infection. Vaccine. 2010;28:3285–90.
Article
PubMed
Google Scholar
Ridda I, Yin JK, King C, Raina MC, McIntyre P. The importance of pertussis in older adults: a growing case for reviewing vaccination strategy in the elderly. Vaccine. 2012;30:6745–52.
Article
PubMed
Google Scholar
Gil A, Oyaguez I, Carrasco P, Gonzalez A. Hospital admissions for pertussis in Spain, 1995-1998. Vaccine. 2001;19:4791–4.
Article
CAS
PubMed
Google Scholar
Halperin SA, Scheifele D, de Serres G, Noya F, Meekison W, Zickler P, et al. Immune responses in adults to revaccination with a tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine 10 years after a previous dose. Vaccine. 2012;30:974–82.
Article
CAS
PubMed
Google Scholar
Taylor DN, Pollard RA, Blake PA. Typhoid in the United States and the risk to the international traveler. J Infect Dis. 1983;148:599–602.
Article
CAS
PubMed
Google Scholar
Hennessy S, Liu Z, Tsai TF, Strom BL, Wan CM, Liu HL, et al. Effectiveness of live-attenuated Japanese encephalitis vaccine (SA14-14-2): a case-control study. Lancet. 1996;347:1583–6.
Article
CAS
PubMed
Google Scholar
Haynes L. The effect of aging on cognate function and development of immune memory. Curr Opin Immunol. 2005;17:476–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Haynes L, Eaton SM, Burns EM, Randall TD, Swain SL. CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly. Proc Natl Acad Sci U S A. 2003;100:15053–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Stoffel M, Lievens M, Dieussaert I, Martin I, Andre F. Immunogenicity of Twinrix in older adults: a critical analysis. Expert Rev Vaccines. 2003;2:9–14.
Article
CAS
PubMed
Google Scholar
Wolters B, Junge U, Dziuba S, Roggendorf M. Immunogenicity of combined hepatitis a and B vaccine in elderly persons. Vaccine. 2003;21:3623–8.
Article
CAS
PubMed
Google Scholar
Fisman DN, Agrawal D, Leder K. The effect of age on immunologic response to recombinant hepatitis B vaccine: a meta-analysis. Clin Infect Dis. 2002;35:1368–75.
Article
PubMed
Google Scholar
Rafferty E, Duclos P, Yactayo S, Schuster M. Risk of yellow fever vaccine-associated viscerotropic disease among the elderly: a systematic review. Vaccine. 2013;31:5798–805.
Article
PubMed
Google Scholar
Wiersma LC, Rimmelzwaan GF, de Vries RD. Developing universal influenza vaccines: hitting the nail, not just on the head. Vaccines (Basel). 2015;3:239–62.
Article
Google Scholar
Feldman C, Anderson R. Review: current and new generation pneumococcal vaccines. J Inf Secur. 2014;69:309–25.
Google Scholar
Harpaz R, Ortega-Sanchez IR, Seward JF. Prevention of herpes zoster: recommendations of the advisory committee on immunization practices (ACIP). MMWR Recomm Rep. 2008;57:1–30.
PubMed
Google Scholar
Hales CM, Harpaz R, Ortega-Sanchez I, Bialek SR. Update on recommendations for use of herpes zoster vaccine. MMWR Morb Mortal Wkly Rep. 2014;63:729–31.
PubMed
Google Scholar
Leroux-Roels I, Leroux-Roels G, Clement F, Vandepapeliere P, Vassilev V, Ledent E, et al. A phase 1/2 clinical trial evaluating safety and immunogenicity of a varicella zoster glycoprotein e subunit vaccine candidate in young and older adults. J Infect Dis. 2012;206:1280–90.
Article
CAS
PubMed
Google Scholar
Chlibek R, Bayas JM, Collins H, de la Pinta ML, Ledent E, Mols JF, et al. Safety and immunogenicity of an AS01-adjuvanted varicella-zoster virus subunit candidate vaccine against herpes zoster in adults >=50 years of age. J Infect Dis. 2013;208:1953–61.
Article
CAS
PubMed
Google Scholar
Stadtmauer EA, Sullivan KM, Marty FM, Dadwal SS, Papanicolaou GA, Shea TC, et al. A phase 1/2 study of an adjuvanted varicella-zoster virus subunit vaccine in autologous hematopoietic cell transplant recipients. Blood. 2014;124:2921–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Berkowitz EM, Moyle G, Stellbrink HJ, Schurmann D, Kegg S, Stoll M, et al. Safety and immunogenicity of an adjuvanted herpes zoster subunit candidate vaccine in HIV-infected adults: a phase 1/2a randomized, placebo-controlled study. J Infect Dis. 2015;211:1279–87.
CAS
PubMed
Google Scholar
Lal H, Cunningham AL, Godeaux O, Chlibek R, Diez-Domingo J, Hwang SJ, et al. Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. N Engl J Med. 2015;372:2087–96.
Article
PubMed
Google Scholar
Cunningham AL, Lal H, Kovac M, Chlibek R, Hwang SJ, Diez-Domingo J, et al. Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older. N Engl J Med. 2016;375:1019–32.
Article
CAS
PubMed
Google Scholar
Fleming DM, Taylor RJ, Lustig RL, Schuck-Paim C, Haguinet F, Webb DJ, et al. Modelling estimates of the burden of respiratory Syncytial virus infection in adults and the elderly in the United Kingdom. BMC Infect Dis. 2015;15:443.
Article
PubMed
PubMed Central
Google Scholar
Shinefield H, Black S, Fattom A, Horwith G, Rasgon S, Ordonez J, et al. Use of a Staphylococcus Aureus conjugate vaccine in patients receiving hemodialysis. N Engl J Med. 2002;346:491–6.
Article
PubMed
Google Scholar
Fowler VG, Allen KB, Moreira ED, Moustafa M, Isgro F, Boucher HW, et al. Effect of an investigational vaccine for preventing Staphylococcus Aureus infections after cardiothoracic surgery: a randomized trial. JAMA. 2013;309:1368–78.
Article
CAS
PubMed
Google Scholar
Swanson KA, Schmitt HJ, Jansen KU, Anderson AS. Adult vaccination. Hum Vaccin Immunother. 2015;11:150–5.
Article
PubMed
Google Scholar
Cross AS, Chen WH, Levine MM. A case for immunization against nosocomial infections. J Leukoc Biol. 2008;83:483–8.
Article
CAS
PubMed
Google Scholar
Michel JP, Chidiac C, Grubeck-Loebenstein B, Johnson RW, Lambert PH, Maggi S, et al. Advocating vaccination of adults aged 60 years and older in Western Europe: statement by the joint vaccine working Group of the European Union Geriatric Medicine Society and the International Association of Gerontology and Geriatrics-European Region. Rejuvenation Res. 2009;12:127–35.
Article
PubMed
Google Scholar
Michel JP, Lang PO, Baeyens JP. Flu vaccination policy in old adults: need for harmonization of national public health recommendations throughout Europe. Vaccine. 2009;27:182–3.
Article
PubMed
Google Scholar
Esposito S, Bonanni P, Maggi S, Tan L, Ansaldi F, Lopalco PL, et al. Recommended immunization schedules for adults: clinical practice guidelines by the Escmid vaccine study group (EVASG), European geriatric medicine society (EUGMS) and the world Association for Infectious Diseases and Immunological Disorders (WAidid). Hum Vaccin Immunother. 2016;12:1777–94.
PubMed
PubMed Central
Google Scholar
European Centre for Disease Prevention and Control. Seasonal influenza vaccination in Europe. Vaccination recommendations and coverage rates in the EU member states for eight influenza seasons: 2007-2008 to 2014-2015. 2017. https://ecdc.europa.eu/sites/portal/files/documents/influenza-vaccination-2007%E2%80%932008-to-2014%E2%80%932015.pdf. Accessed 27 July 2017.
Kanitz EE, Wu LA, Giambi C, Strikas RA, Levy-Bruhl D, Stefanoff P, et al. Variation in adult vaccination policies across Europe: an overview from VENICE network on vaccine recommendations, funding and coverage. Vaccine. 2012;30:5222–8.
Article
PubMed
Google Scholar