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Fig. 1 | Immunity & Ageing

Fig. 1

From: Molecular changes associated with increased TNF-α-induced apoptotis in naïve (TN) and central memory (TCM) CD8+ T cells in aged humans

Fig. 1

TNF-α-induced apoptosis in TN and TCM CD8+ T cells. Activated purified TN and TCM CD8+ T cells subsets were incubated in the absence or presence of TNF-α for 48 h and apoptosis was measured by TUNEL assay using FACSCalibur. Ten thousand cells were acquired. Data for spontaneous and TNF-α-induced apoptosis from 10 young and 10 aged subjects are presented as percent of TUNEL positive cells. A significantly increased (P < 0.001) apoptosis was observed in aged subjects. No significant difference was observed in spontaneous apoptosis between young and aged subjects

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