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Fig. 5 | Immunity & Ageing

Fig. 5

From: Molecular changes associated with increased TNF-α-induced apoptotis in naïve (TN) and central memory (TCM) CD8+ T cells in aged humans

Fig. 5

TNF-α-induced NF-κB activity in TN and TCM CD8+ T cells by ELISA-based DNA binding assay. Purified TN and TCM CD8+ T cell subsets were activated with TNF-α for 10 min and NF-κB activity was measured by ELISA-based DNA binding activity. Data are shown from five young and five aged subjects. A significantly lower (P < 0.01) NF-κB activation was observed in aged subjects

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