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Table 1 Characteristics of the study population

From: Thymus and activation-regulated chemokine (TARC)/CCL17 and IgE are associated with elderly asthmatics

  Normal Asthma
Number of subjects (female/male) 106(62/44) 121 (66/55)
Age (years) 45.3 ± 12.7(19~ 72) 50.8 ± 16.7 (15~ 84)
FEV1§ 4.1 ± 0.9 (2.7~ 5.3)** 2.1 ± 0.8 (1~ 4)**
FEV1§ (% predicted) 101.6 ± 11.9 (87.1~ 121.3)* 81.4 ± 22.2 (34~ 125)*
FVC (% predicted) 95.2 ± 11.5 (77.9~ 112.9) 91.3 ± 17.8 (40~ 140)
FEV1/FVC (%) 91.6 ± 4.9 (84.8~ 97.9)** 71.9 ± 14.2 (35~ 98)**
Blood cells Neutrophils 55.3 ± 9.7 (28.5~ 75.4) 59.5 ± 14.3 (27~ 92)
Lymphocytes 35.7 ± 9.3 (20~ 67.3)** 26.8 ± 11.0 (4~ 52)**
Monocytes 6.7 ± 3.2 (2.0~ 19.0)** 7.0 ± 2.7 (1~ 17)**
Eosinophils 2.0 ± 1.4 (0~ 6.0)** 5.7 ± 8.4 (0~ 55)**
Basophils 0.3 ± 0.3(0~ 1.3)* 0.5 ± 0.5 (0~ 4)*
BALF cells Neutrophils 2.0 ± 1.6 (0~ 5.1)** 16.6 ± 26.7 (0~ 90)**
Lymphocytes 10.6 ± 8.4 (1.0~ 29.2) 16.9 ± 17.0 (0~ 69)
Macrophage 86.2 ± 10.4 (62.0~ 99.0)** 59.9 ± 27.8 (3~ 95)**
Eosinophils 0.2 ± 0.6 (0~ 1.9) 3.9 ± 8.5 (0~ 52)
Basophils 0 ± 0 (0~ 0) 0.04 ± 0.1(0~ 1)
Epithelial cells 0.8 ± 1.0 (0~ 2.5) 2.38 ± 9.6 (0~ 86)
  Total IgE 92.8 ± 143.4(2.2~ 694.2)** 376.4 ± 612.2 (2~ 3000)**
  Der p 1-specific IgE 0.8 ± 2.1(0~ 10.4)* 4.1 ± 15.3 (0~ 100)*
IgE Der p 1-specific IgE (class) 0.4 ± 1.0(0~ 3) 0.62 ± 1.2 (0~ 5)
  Der f 1-specific IgE 1.5 ± 4.4(0~ 23.4)** 7.3 ± 19.5 (0~ 100)**
  Der f 1-specific IgE (class) 0.8 ± 1.2(0~ 4) 1.2 ± 1.5 (0~ 5)
  1. FEV1§: forced expiratory volume in 1 second
  2. FVC: forced vital capacity
  3. Data are expressed as the means ± SD (the lowest value ~ the highest value)
  4. *p < 0.05 and **p < 0.01 indicate statistically significant differences between the normal and asthma groups