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Table 1 Characteristics of the study population

From: Thymus and activation-regulated chemokine (TARC)/CCL17 and IgE are associated with elderly asthmatics

 

Normal

Asthma

Number of subjects (female/male)

106(62/44)

121 (66/55)

Age (years)

45.3 ± 12.7(19~ 72)

50.8 ± 16.7 (15~ 84)

FEV1§

4.1 ± 0.9 (2.7~ 5.3)**

2.1 ± 0.8 (1~ 4)**

FEV1§ (% predicted)

101.6 ± 11.9 (87.1~ 121.3)*

81.4 ± 22.2 (34~ 125)*

FVC (% predicted)

95.2 ± 11.5 (77.9~ 112.9)

91.3 ± 17.8 (40~ 140)

FEV1/FVC (%)

91.6 ± 4.9 (84.8~ 97.9)**

71.9 ± 14.2 (35~ 98)**

Blood cells

Neutrophils

55.3 ± 9.7 (28.5~ 75.4)

59.5 ± 14.3 (27~ 92)

Lymphocytes

35.7 ± 9.3 (20~ 67.3)**

26.8 ± 11.0 (4~ 52)**

Monocytes

6.7 ± 3.2 (2.0~ 19.0)**

7.0 ± 2.7 (1~ 17)**

Eosinophils

2.0 ± 1.4 (0~ 6.0)**

5.7 ± 8.4 (0~ 55)**

Basophils

0.3 ± 0.3(0~ 1.3)*

0.5 ± 0.5 (0~ 4)*

BALF cells

Neutrophils

2.0 ± 1.6 (0~ 5.1)**

16.6 ± 26.7 (0~ 90)**

Lymphocytes

10.6 ± 8.4 (1.0~ 29.2)

16.9 ± 17.0 (0~ 69)

Macrophage

86.2 ± 10.4 (62.0~ 99.0)**

59.9 ± 27.8 (3~ 95)**

Eosinophils

0.2 ± 0.6 (0~ 1.9)

3.9 ± 8.5 (0~ 52)

Basophils

0 ± 0 (0~ 0)

0.04 ± 0.1(0~ 1)

Epithelial cells

0.8 ± 1.0 (0~ 2.5)

2.38 ± 9.6 (0~ 86)

 

Total IgE

92.8 ± 143.4(2.2~ 694.2)**

376.4 ± 612.2 (2~ 3000)**

 

Der p 1-specific IgE

0.8 ± 2.1(0~ 10.4)*

4.1 ± 15.3 (0~ 100)*

IgE

Der p 1-specific IgE (class)

0.4 ± 1.0(0~ 3)

0.62 ± 1.2 (0~ 5)

 

Der f 1-specific IgE

1.5 ± 4.4(0~ 23.4)**

7.3 ± 19.5 (0~ 100)**

 

Der f 1-specific IgE (class)

0.8 ± 1.2(0~ 4)

1.2 ± 1.5 (0~ 5)

  1. FEV1§: forced expiratory volume in 1 second
  2. FVC: forced vital capacity
  3. Data are expressed as the means ± SD (the lowest value ~ the highest value)
  4. *p < 0.05 and **p < 0.01 indicate statistically significant differences between the normal and asthma groups