Anti-cytomegalovirus IgG antibody titer is positively associated with advanced T cell differentiation and coronary artery disease in end-stage renal disease

Table 2 Correlations between HCMV-specific IgG titer with levels of immune cells among ESRD patients

	Cell frequency		Absolute cell number
	R	p value	R	p value
CD4+ T cells
Naïve T cells	−0.33	NS	−0.05	NS
Stem Memory T cells	−0.03	NS	−0.12	NS
Central Memory T cells	−0.12	0.013*	−0.13	0.007*
Effector Memory T cells	0.14	0.006*	0.06	NS
Terminally Differentiated T cells	0.11	0.035*	0.010	0.003*
CD28 null cells	0.15	0.002*	0.12	0.02*
CD8+ T cells
Naïve T cells	−0.15	0.003*	−0.18	< 0.001*
Stem Memory T cells	0.006	NS	−0.16	0.002*
Central Memory T cells	−0.10	0.039*	−0.15	0.003*
Effector Memory T cells	−0.03	NS	−0.03	NS
Terminally Differentiated T cells	0.20	< 0.001*	0.09	0.07
Monocytes
Classical Monocytes	0.02	NS	0.04	NS
Intermediate Monocytes	0.01	NS	0.04	NS
Non-Classical Monocytes	−0.03	NS	−0.006	NS

Pearson correlation was applied to investigate the relationship between log transformed HCMV-specific IgG titer and immune cell levels, including percentages as well as absolute cell counts of naïve (T_NAIVE), stem cell memory (T_SCM), central memory (T_CM), effector memory (T_EM), terminally differentiated (T_EMRA) subsets and three monocyte subsets (classical monocytes, intermediate monocytes, non-classical monocytes)
NS non-significant, P value > 0.1
*p value < 0.05