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Table 3 Association between HCMV-specific IgG quintile and coronary artery disease or cardiovascular disease

From: Anti-cytomegalovirus IgG antibody titer is positively associated with advanced T cell differentiation and coronary artery disease in end-stage renal disease

Variables in model (independent variable: CAD) OR (95% CI) P value
 Model 1
  Age 1.03(1.01–1.05) 0.01*
  Gender (Male) 1.43(0.90–2.29) 0.14
  Diabetes 2.90(1.82–4.64) < 0.001*
  HCMV-specific IgG quintile 1.25(1.06–1.48) 0.007*
 Model 2
  Age 1.04(1.01–1.06) 0.003*
  Gender (Male) 1.39(0.86–2.25) 0.18
  Diabetes 2.87(1.77–4.64) < 0.001*
  Albumin (g/dL) 1.44(0.67–3.12) 0.35
  Hemoglobin (g/dL) 1.17(0.97–1.43) 0.10
  Ca × P product (mg2/dL2) 1.01 (1.0–1.03) 0.27
  hs-CRP (mg/dL) 1.37(1.12–1.67) 0.002*
  HCMV-specific IgG quintile 1.27(1.07–1.51) 0.007*
Variables in model (independent variable: CVD) OR (95% CI) P value
 Model 1
  Age 1.04(1.02–1.06) < 0.001*
  Gender (Male) 1.36(0.88–2.11) 0.17
  Diabetes 2.88(1.86–4.48) < 0.001*
  HCMV-specific IgG quintile 1.13(0.97–1.32) 0.13
 Model 2
  Age 1.03(1.02–1.06) < 0.001*
  Gender (Male) 1.32(0.84–2.08) 0.22
  Diabetes 2.84(1.80–4.44) < 0.001*
  Albumin (g/dL) 1.07(0.52–2.16) 0.87
  Hemoglobin (g/dL) 1.20(1.00–1.44) 0.048*
  Ca × P product (mg2/dL2) 1.01 (0.99–1.03) 0.32
  hs-CRP (mg/dL) 1.32(1.08–1.60) 0.005*
  HCMV-specific IgG quintile 1.13(0.96–1.33) 0.13
  1. Multivariable-adjusted logistic regression models, including age, gender, diabetes mellitus, albumin, hemoglobin, calcium phosphate product and high sensitivity-CRP were used to investigate the independent association between HCMV IgG quintile and co-morbidities. *: p value < 0.05