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Table 3 Association between HCMV-specific IgG quintile and coronary artery disease or cardiovascular disease

From: Anti-cytomegalovirus IgG antibody titer is positively associated with advanced T cell differentiation and coronary artery disease in end-stage renal disease

Variables in model (independent variable: CAD)

OR (95% CI)

P value

 Model 1

  Age

1.03(1.01–1.05)

0.01*

  Gender (Male)

1.43(0.90–2.29)

0.14

  Diabetes

2.90(1.82–4.64)

< 0.001*

  HCMV-specific IgG quintile

1.25(1.06–1.48)

0.007*

 Model 2

  Age

1.04(1.01–1.06)

0.003*

  Gender (Male)

1.39(0.86–2.25)

0.18

  Diabetes

2.87(1.77–4.64)

< 0.001*

  Albumin (g/dL)

1.44(0.67–3.12)

0.35

  Hemoglobin (g/dL)

1.17(0.97–1.43)

0.10

  Ca × P product (mg2/dL2)

1.01 (1.0–1.03)

0.27

  hs-CRP (mg/dL)

1.37(1.12–1.67)

0.002*

  HCMV-specific IgG quintile

1.27(1.07–1.51)

0.007*

Variables in model (independent variable: CVD)

OR (95% CI)

P value

 Model 1

  Age

1.04(1.02–1.06)

< 0.001*

  Gender (Male)

1.36(0.88–2.11)

0.17

  Diabetes

2.88(1.86–4.48)

< 0.001*

  HCMV-specific IgG quintile

1.13(0.97–1.32)

0.13

 Model 2

  Age

1.03(1.02–1.06)

< 0.001*

  Gender (Male)

1.32(0.84–2.08)

0.22

  Diabetes

2.84(1.80–4.44)

< 0.001*

  Albumin (g/dL)

1.07(0.52–2.16)

0.87

  Hemoglobin (g/dL)

1.20(1.00–1.44)

0.048*

  Ca × P product (mg2/dL2)

1.01 (0.99–1.03)

0.32

  hs-CRP (mg/dL)

1.32(1.08–1.60)

0.005*

  HCMV-specific IgG quintile

1.13(0.96–1.33)

0.13

  1. Multivariable-adjusted logistic regression models, including age, gender, diabetes mellitus, albumin, hemoglobin, calcium phosphate product and high sensitivity-CRP were used to investigate the independent association between HCMV IgG quintile and co-morbidities. *: p value < 0.05