Fig. 6

Transferred CD8 cells from naïve aged and young mice clear virus with similar kinetics. a CD8 T cells from naive aged or young mice were enriched from splenocytes using negative selection, adoptively transferred into individual T cell deficient βδ−/− mice, infected with influenza virus, and the lungs were harvested at days 8 and 10 post-infection to determine viral titers. b Summary graphs of the viral foci/lung on days 8 and 10 post infection. Data from two independent experiments, pooled for statistical analysis, are represented in separate shades. Bars represent the median. Viral titers on day 8 or on day 10 in the two groups did not differ significantly (p > 0.05). Data were analyzed by Mann-Whitney Test. c Graph of the viral foci/lung on days 8 and 10 post infection for control individual WT C57BL/6 mice and individual T cell deficient βδ−/− mice that did not receive adoptively transferred CD8 T cells