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Table 3 Expressions of autophagy-related genes of the survived and patients dead within 28 days after treatment

From: Expression changes of autophagy-related proteins in AKI patients treated with CRRT and their effects on prognosis of adult and elderly patients

 

Survived patient (n = 197)

Dead patient (n = 50)

p

LC3-II

0.93 ± 0.22

1.32 ± 0.15

< 0.001

Atg-5

0.88 ± 0.29

1.20 ± 0.12

< 0.001

Beclin-1

1.02 ± 0.31

1.55 ± 0.16

< 0.001

  1. LC3-II, Atg-5 and Beclin-1 expressions measured through qRT-PCR in the monocytes showed that the expressions of autophagy-related proteins were significantly elevated in patients died after one to three weeks after the treatment when compared to survived patients