Fig. 1
From: Crocetin attenuates inflammation and amyloid-β accumulation in APPsw transgenic mice
Effect of crocetin on cell viability and the levels of Aβ42 and Aβ40 in APPsw-transfected cells. Cells were treated with crocetin at the indicated concentrations for 8 h. Pb (80 mg/L) was employed as a positive control. Cell viability was measured using MTT assay, and the levels of Aβ42 and Aβ40 in cultured medium were measured using a sandwich ELISA. Crocetin did not affect the viability of APPsw-transfected cells (a), but reduced the levels of Aβ40 (b) and Aβ42 (c) in a dose-dependent manner. (n = 4) ∗ p < 0.05; ∗∗ p < 0.01; ∗∗∗ p < 0.001