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Fig. 3 | Immunity & Ageing

Fig. 3

From: Aged mice display altered numbers and phenotype of basophils, and bone marrow-derived basophil activation, with a limited role for aging-associated microbiota

Fig. 3

Effect of microbiota transfer of young and old mice to germ-free mice on basophil frequencies and phenotype in the bone marrow and the spleen. a Quantification of mean frequencies and absolute numbers of BM basophils or median fluorescence intensity (MFI) on BM basophils of FcεRIα, CD200R3, CD123, IL-33R, and TSLPR. b Quantification of mean frequencies of spleen basophils or MFI on spleen basophils of FcεRIα, CD200R3, CD123, TSLPR, IL-33R, and CD11b. c Quantification of mean frequencies and absolute numbers of BM basophils or median fluorescence intensity (MFI) on BM basophils of FcεRIα, CD200R3, CD123, IL-33R, and TSLPR. d Quantification of mean frequencies of spleen basophils or MFI on spleen basophils of FcεRIα, CD200R3, CD123, TSLPR, IL-33R, and CD11b. Data represent n = 10 mice per group (panel a and b) and n = 5 mice per group (panel c and d). BM = bone marrow; Conv = conventional; GF = germ-free; O = microbiota derived from old mouse; Y = microbiota derived from young mouse. * = p < 0.05; ** = p < 0.01

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Immunity & Ageing

ISSN: 1742-4933

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