Table 1 Study subject characteristics
Young cohort (N = 29) | Healthy elderly cohort (N = 22) | p | |
|---|---|---|---|
Demography | |||
Age | 27.97 (23–33) | 72.41 (65–84) | **** |
Gender | 18 females (63.3%) | 10 females (45.5%) | ns |
BMI | 22.8 (16.2–29.1) | 23.6 (17.4–32.6) | ns |
Physical activity (% of time) | |||
Sedentary | 60.3 (46.5–98.9) | 60.2 (43.4–92.5) | ns |
Light activity | 35.1 (0.9–47.9) | 35.2 (7.4–48.4) | ns |
Moderate activity | 4.5 (0.1–11.1) | 3.8 (0.1–15.4) | ns |
Vigorous activity | 0.1 (0–1.8) | 0.8 (0–12.1) | ns |
Clinical | |||
CMV positivity | 13 (45%) | 22 (100%) | **** |
CD4/CD8 ratio | 1.33 (0.62–2.42) | 2.94 (0.52–14.71) | ** |
CRP (mg/L) | 1.2 (0.2–4.1) | 2.7 (0.3–9.3) | ** |
Comorbidities | – | 0.36 (0–1) | – |
MMSE/MoCA | – | 28 (22–30) / 25.59 (18–30) | – |
Pre/Post FEV1/FVC | – | 0.73 (0.5–0.91)/0.71 (0.29–0.85) | – |
Medications | – | 1.05 (0–4) | – |
Hospitalizations | – | 0 | – |
MNA | – | 12.8 (11–14) | – |