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Table 1 Study subject characteristics

From: Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine

  Young cohort (N = 29) Healthy elderly cohort (N = 22) p
Demography
 Age 27.97 (23–33) 72.41 (65–84) ****
 Gender 18 females (63.3%) 10 females (45.5%) ns
 BMI 22.8 (16.2–29.1) 23.6 (17.4–32.6) ns
Physical activity (% of time)
 Sedentary 60.3 (46.5–98.9) 60.2 (43.4–92.5) ns
 Light activity 35.1 (0.9–47.9) 35.2 (7.4–48.4) ns
 Moderate activity 4.5 (0.1–11.1) 3.8 (0.1–15.4) ns
 Vigorous activity 0.1 (0–1.8) 0.8 (0–12.1) ns
Clinical
 CMV positivity 13 (45%) 22 (100%) ****
 CD4/CD8 ratio 1.33 (0.62–2.42) 2.94 (0.52–14.71) **
 CRP (mg/L) 1.2 (0.2–4.1) 2.7 (0.3–9.3) **
 Comorbidities 0.36 (0–1)
 MMSE/MoCA 28 (22–30) / 25.59 (18–30)
 Pre/Post FEV1/FVC 0.73 (0.5–0.91)/0.71 (0.29–0.85)
 Medications 1.05 (0–4)
 Hospitalizations 0
 MNA 12.8 (11–14)
  1. BMI body mass index, CMV human cytomegalovirus, CRP C-reactive protein, MMSE mini mental state examination, MoCA Montreal cognitive assessment, FEV forced expiratory volume, FVC forced vital capacity, pre/post inhalation of a bronchodilator, MNA mini nutritional assessment score. Physical activity was measured during 2 weeks using actigraphy watches (Phillips Respironics). Comorbidities are expressed as the number of diagnosed conditions, medications are defined as the number of prescribed drugs and hospitalizations is the number of time the individual have been hospitalized in the past year