Fig. 3

a Cumulative percentage of de novo DSA positivity in the cohort of recipients developing a donor specific humoral immune response: n = 12 in the older cohort and n = 6 in the pediatric cohort. b Comparison of immunosuppressive medication (Cyclosporine = Cyc, Tacrolimus = Tac) at time point of detection of de novo DSA between recipients with and without de novo donor specific humoral immune response in both cohorts, i.e. older and pediatric patients. Comparison using Chi-square test