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Table 3 Correlations for cytokine concentrationsa with BMI, WC, hsCRP, and sports adjusted for age and sex

From: Cytokines for evaluation of chronic inflammatory status in ageing research: reliability and phenotypic characterisation

Biomarker BMI (kg/cm2) Waist Circumference (cm) hsCRP (ug/ml) Reported sports activitiesb (hours/week)
N ρc 95% CId N ρc 95% CId N ρc 95% CId N ρc 95% CId
IL-1β 102 −0.19 − 0.37, 0.01 102 −0.15 − 0.33, 0.05 76 0.06 −0.17, 0.28 79 0.09 −0.14, 0.3
P-value   0.06    0.15    0.62    0.46  
IL-2 159 0.04 −0.11, 0.2 159 0.08 −0.07, 0.24 126 −0.02 − 0.2, 0.15 143 0.07 −0.1, 0.23
P-value   0.59    0.30    0.78    0.42  
IL-4 175 −0.06 −0.21, 0.09 175 −0.06 −0.21, 0.09 137 0.03 −0.14, 0.2 143 0.03 −0.14, 0.19
P-value   0.44    0.69    0.42    0.76  
IL-6 207 0.36 0.23, 0.47 207 0.41 0.28, 0.51 164 0.53 0.41, 0.63 207 −0.12 −0.26, 0.01
P-value   <.0001    <.0001    <.0001    0.08  
IL-8 207 0.05 −0.08, 0.19 207 0.04 −0.1, 0.18 164 0.06 −0.1, 0.21 207 0 −0.14, 0.14
P-value   0.44    0.58    0.46    0.98  
IL-10 207 0 −0.14, 0.13 207 0.02 −0.12, 0.15 164 0.19 0.03, 0.33 207 0.04 −0.1, 0.17
P-value   0.96    0.82    0.02    0.60  
IL-12p70 205 0.06 −0.08, 0.19 205 0.10 −0.04, 0.23 162 −0.02 − 0.17, 0.14 194 0.07 −0.08, 0.21
P-value   0.43    0.16    0.82    0.36  
IL-13 191 0.06 −0.09, 0.2 191 0.06 −0.09, 0.2 152 0.12 −0.04, 0.28 167 0.04 −0.12, 0.19
P-value   0.44    0.45    0.14    0.63  
IFN-γ 207 0.04 −0.1, 0.17 207 0.09 −0.05, 0.22 164 0.23 0.08, 0.37 207 0.01 −0.12, 0.15
P-value   0.60    0.22    0.004    0.84  
TNF- α 207 0.20 0.07, 0.33 207 0.16 0.03, 0.29 164 0.22 0.07, 0.36 207 −0.15 −0.28, −0.02
P-value   0.004    0.02    0.004    0.03  
  1. aMean cytokine concentrations from both measurements bSports in winter with first blood sample from October–March. cSpearman partial correlation coefficient. dBased on Fisher’s z transformation Abbreviations: BMI Body mass index, CI Confidence interval, hsCRP High sensitivity c-reactive protein, IL-1β Interleukin 1-beta, IL-2 Interleukin 2, IL-4 Interleukin 4, IL-8 Interleukin 8, IL-10 Interleukin 10, IL-12p70 Interleukin 12p70, IL-13 Interleukin 13, IFN-γ Interferon gamma, IQR Interquartile range, TNF-α Tumor necrosis factor alpha, WC Waist circumference