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Table 3 Cytokines/inflammatory markers according to spine osteoporosis status

From: Inflammatory markers and bone health in postmenopausal women: a cross-sectional overview

Markers Osteoporotic Osteopenic Healthy F-value P-value
  (n = 13) (n = 34) (n = 39)
IL-1β (pg/ml) 7.22(17.59) 2.06(4.88) 1.52(4.21) 2.670 0.075
IFN-α2 (pg/ml) 35.28(48.19) 9.96(18.95) 18.42(26.63) 3.783 0.027
IFN-γ (pg/ml) 153.38(222.32) 50.67(58.72) 57.91(73.24) 4.956 0.009
TNF-α (pg/ml) 2.01(2.70) 1.83(3.72) 3.19(6.02) 0.795 0.455
MCP-1 (pg/ml) 221.36(100.46) 176.66(43.13) 200.73(55.68) 3.000 0.055
IL-6 (pg/ml) 3.22(4.29) 3.14(11.26) 3.09(10.61) 0.001 0.999
IL-8 (pg/ml) 23.85(42.34) 11.19(11.84) 10.66(14.99) 2.220 0.115
IL-10 (pg/ml) 4.62(15.67) 0.57(1.52) 0.75(1.95) 2.261 0.111
IL-12p70 (pg/ml) 6.47(17.03) 1.86(5.74) 0.48(1.36) 3.128 0.049
IL-17A (pg/ml) 102.40(227.62) 41.75(79.92) 31.11(45.72) 2.303 0.106
IL-18 (pg/ml) 153.45(72.70) 133.21(69.18) 144.98(51.66) 0.600 0.551
IL-23 (pg/ml) 103.40(173.69) 56.60(91.14) 42.84(55.70) 1.970 0.146
IL-33 (pg/ml) 13.88(37.44) 0.79(3.32) 2.83(11.19) 3.147 0.048
CRP (μg/ml) 0.75(1.07) 1.39(1.36) 2.04(2.05) 3.219 0.044
Ferritin (μg/L) 149.46(116.16) 124.45(94.57) 156.29(103.72) 0.890 0.415
  1. IL Interleukin, IFN Interferon, MCP Monocyte chemoattractant protein, CRP C-reactive protein. Osteoporosis status was according to WHO classification [25]. Variables are reported as mean values with their standard deviation (SD). Number of participants (n). Significant values are in bold text