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Table 3 Cytokines/inflammatory markers according to spine osteoporosis status

From: Inflammatory markers and bone health in postmenopausal women: a cross-sectional overview

Markers

Osteoporotic

Osteopenic

Healthy

F-value

P-value

 

(n = 13)

(n = 34)

(n = 39)

IL-1β (pg/ml)

7.22(17.59)

2.06(4.88)

1.52(4.21)

2.670

0.075

IFN-α2 (pg/ml)

35.28(48.19)

9.96(18.95)

18.42(26.63)

3.783

0.027

IFN-γ (pg/ml)

153.38(222.32)

50.67(58.72)

57.91(73.24)

4.956

0.009

TNF-α (pg/ml)

2.01(2.70)

1.83(3.72)

3.19(6.02)

0.795

0.455

MCP-1 (pg/ml)

221.36(100.46)

176.66(43.13)

200.73(55.68)

3.000

0.055

IL-6 (pg/ml)

3.22(4.29)

3.14(11.26)

3.09(10.61)

0.001

0.999

IL-8 (pg/ml)

23.85(42.34)

11.19(11.84)

10.66(14.99)

2.220

0.115

IL-10 (pg/ml)

4.62(15.67)

0.57(1.52)

0.75(1.95)

2.261

0.111

IL-12p70 (pg/ml)

6.47(17.03)

1.86(5.74)

0.48(1.36)

3.128

0.049

IL-17A (pg/ml)

102.40(227.62)

41.75(79.92)

31.11(45.72)

2.303

0.106

IL-18 (pg/ml)

153.45(72.70)

133.21(69.18)

144.98(51.66)

0.600

0.551

IL-23 (pg/ml)

103.40(173.69)

56.60(91.14)

42.84(55.70)

1.970

0.146

IL-33 (pg/ml)

13.88(37.44)

0.79(3.32)

2.83(11.19)

3.147

0.048

CRP (μg/ml)

0.75(1.07)

1.39(1.36)

2.04(2.05)

3.219

0.044

Ferritin (μg/L)

149.46(116.16)

124.45(94.57)

156.29(103.72)

0.890

0.415

  1. IL Interleukin, IFN Interferon, MCP Monocyte chemoattractant protein, CRP C-reactive protein. Osteoporosis status was according to WHO classification [25]. Variables are reported as mean values with their standard deviation (SD). Number of participants (n). Significant values are in bold text