Six weeks of strength endurance training decreases circulating senescence-prone T-lymphocytes in cytomegalovirus seropositive but not seronegative older women

Table 1 Absolute counts and Percentage of T-cell subsets at baseline with respect to CMV serostatus

Parameter		CMV − (n = 34)	CMV + (n = 63)	p value^a
T-cell subset
CD8+ T-cells
CD8 + CD28 + CD57− (naïve)	cells/μL	130.29 (88.50)	154.60 (117.30)	0.111
CD8 + CD28 + CD57− (naïve)	%	73.60 (24.40)	54.90 (26.40)	< 0.001
CD8 + CD28 − CD57− (memory)	cells/μL	30.00 (52.50)	90.00 (100)	< 0.001
CD8 + CD28 − CD57− (memory)	%	20.30 (18.53)	29.50 (22.30)	< 0.001
CD8 + CD57+ (SPC)	cells/μL	5.81 (17.30)	27.06 (38.30)	< 0.001
CD8 + CD57+ (SPC)	%	4.00 (7.15)	7.15 (13.08)	0.010
CD8 + CD28 − CD57+ (SPC)	cells/μL	4.90 (15.70)	26.38 (37.40)	< 0.001
CD8 + CD28 − CD57+ (SPC)	%	2.90 (6.25)	6.35 (11.98)	0.004
CD8 + CD28 + CD57+ (SPC)	cells/μL	0.84 (1.40)	0.65 (1.40)	0.913
CD8 + CD28 + CD57+ (SPC)	%	0.30 (0.80)	0.20 (0.40)	0.065
CD8− T-cells
CD8 − CD28 + CD57 − (naive)	cells/μL	641.91 (310.20)	650.27 (343.30)	0.844
CD8 − CD28 + CD57 − (naive)	%	99.40 (0.90)	96.50 (4.70)	< 0.001
CD8 − CD28 − CD57− (memory)	cells/μL	0.00 (10.00)	20.00 (20.00)	< 0.001
CD8 − CD28 − CD57− (memory)	%	0.45 (0.65)	2.00 (4.00)	< 0.001
CD8 − CD57+ (SPC)	cells/μL	0.66 (1.50)	6.92 (13.80)	< 0.001
CD8 − CD57+ (SPC)	%	0.10 (0.20)	0.90 (2.00)	< 0.001
CD8 − CD28 − CD57 + (SPC)	cells/μL	0.00 (0.80)	6.12 (10.00)	< 0.001
CD8 − CD28 − CD57 + (SPC)	%	0.00 (0.13)	0.80 (1.70)	< 0.001
CD8 − CD28 + CD57 + (SPC)	cells/μL	0.56 (0.90)	0.81 (1.80)	0.081
CD8 − CD28 + CD57 + (SPC)	%	0.10 (0.10)	0.10 (0.40)	0.151

Note: The values denote median (Interquartile range). CMV cytomegalovirus, SPC senescence-prone cells. T-cell subsets were expressed as percentages within the CD3 + CD8+ or CD3 + CD8− T-cells or absolute number of cells in peripheral blood (cells/μL). ^aResults of Mann-Whitney U Test

ISSN: 1742-4933